Ricerc@Sapienza

The integration of systems for real-time monitoring of DNA amplification reactions is rather limited, because the heating system, the temperature control and the detection system are usually realized with separate modules. In this work, a lab-on-a-chip system for real-time monitoring of the multiple displacement amplification reaction (MDA) is presented. The amplification and detection unit consists of a system-on-glass (SoG) coupled to a microfluidic chip.

Several studies reported the presence of organic compounds in extraterrestrial environments, thus one of the main objectives of the research in the field of exobiology is the search for organic molecules and compounds in planetary exploration missions and the identification of their biological or non-biological origin. To reach this goal, devices capable of analyzing in-situ material samples searching for organic molecules, amino acids, nucleic acids, polysaccharides and other biological systems molecules are under development.