Thymic epithelial tumors phenotype relies on MIR-145-5p epigenetic regulation
Background: Thymic epithelial tumors (TETs) are rare tumors arising from the thymic epithelium, thymoma and thymic carcinoma being the most frequent subtypes. TET
gene expression profile
Platform for the Hypoxic Analysis of Cell Behavior (HYP-ACB) including Seahorse instrument
Italiano
The Hyp-ACB facility is a complex infrastructure able to measure, under normoxic and hypoxic conditions, the metabolic activity of living cells, with particular attention to the respiratory activity of mitochondria, in parallel with analysis of gene expression. The facility allows monitoring cell metabolism and gene expression under variable oxygen tensions, thus reproducing more closely the cell or tissue microenvironment(s) in both physiological and pathological conditions.
Genetic Landscape of Ultra-Stable Chronic Lymphocytic Leukemia Patients
BACKGROUND:
Chronic lymphocytic leukemia (CLL) has a heterogeneous clinical course. Beside patients requiring immediate treatment, others show an initial indolent phase followed by progression and others do not progress for decades. The latter two subgroups usually display mutated IGHV genes and a favorable FISH profile.