Ricerc@Sapienza

Low age-specific serum levels of AMH, indicating a reduced ovarian reserve, were observed in 12% of long-standing T1D patients, 10% of endometriosis infertile patients and 4% of healthy women. The prevalence of low circulating AMH levels was very similar between T1D and endometriosis infertile patients (12% vs 10%, p>0.05, respectively), whereas the prevalence of reduced ovarian reserve was significantly higher in T1D group compared to control group (12% vs 4%, p<0.05, respectively) and in endometriosis infertile group compared to control group (10% vs 4% p<0.02, respectively).

Objective: To evaluate if the presence of endometriomas impacts on the ovarian reserve as evaluated with antimüllerian hormone (AMH). Design: Systematic review and meta-analysis. Setting: Not applicable. Patient(s): Patients with unoperated endometriomas versus controls without endometriomas. Intervention(s): Electronic databases searched up to June 2017 to identify articles evaluating AMH levels in patients with unoperated endometriomas versus controls without endometriomas.

The aim of the present study was to evaluate the effect of medical treatment of ovarian endometriomas on cyst diameter, associated pain, and ovarian reserve as measured with antral follicle count (AFC) and anti-Mullerian hormone (AMH). In this prospective study, 32 patients with unilateral endometrioma associated with pelvic pain, underwent 6-month medical treatment with dienogest. Before treatment, and at the end of 6 months of treatment, patients underwent evaluation of endometrioma diameter and AFC at transvaginal ultrasonography, measurement of AMH, and evaluation of associated pain.

The aim of the present study was to evaluate the effect of laparoscopic cystectomy on ovarian reserve by means of anti-Müllerian hormone (AMH) serial measurements and to compare AMH values with the number of inadvertently removed follicles in histological specimens. Fifty-two women were enrolled: 34 patients with endometriomas (group 1) and 18 patients with other benign ovarian cysts (group 2). All patients underwent laparoscopic cystectomy performed by a single experienced surgeon.

.Ovarian endometriomas affect 17 to 44% of women with endometriosis, and are often associated with pelvic pain and infertility. Treatment options include expectant management, medical and/or surgical treatment, and in vitro fertilization and embryo transfer (IVF-ET). The choice of treatment depends mostly on the associated symptoms. In most cases, surgery is the preferred choice, since endometriomas do not respond to medical treatment, which may only treat associated pain.