Anti-Müllerian hormone as marker of ovarian reserve in patients with long-standing type 1 diabetes

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Filardi T, Morano S, Tartaglione S, Porpora M G, Tiberti C, Lenzi A, Angeloni A, Anastasi E
ISSN: 0393-974X

Low age-specific serum levels of AMH, indicating a reduced ovarian reserve, were observed in 12% of long-standing T1D patients, 10% of endometriosis infertile patients and 4% of healthy women. The prevalence of low circulating AMH levels was very similar between T1D and endometriosis infertile patients (12% vs 10%, p>0.05, respectively), whereas the prevalence of reduced ovarian reserve was significantly higher in T1D group compared to control group (12% vs 4%, p<0.05, respectively) and in endometriosis infertile group compared to control group (10% vs 4% p<0.02, respectively). Antral follicular count (AFC) did not significantly differ between the study groups.

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