Urinary reference ranges and exposure profile for lithium among an Italian paediatric population
The aims of the present studywere to establish reference values useful in monitoring Lithium(Li) treatment and
to trace environmental Li exposure profiles in paediatric age.
A cross-sectional studywas conducted on a group of healthy Italian children aged 5–11. Data on possible predictors
were assessed through a questionnaire, and Li levels in morning and evening urinary samples were determined
by ICP-MS technique.
The reference intervals for the evening and morning samples were respectively 3.8–51.9 μg L−1 or