Ricerc@Sapienza

We identified three different vascular patterns based on their appearance: (i) the simple tortuosity; (ii) the more complex corkscrew; and iii) the moya moya-like configurations. In the “corkscrew” pattern, we identified a spiral attitude of vessels, while the moya moya-like configuration was characterized by tortuous vessels that end in a “puff of smoke” arrangement that resembles the collateral circulation seen in moya moya syndrome..

Purpose: Only a few reports in the literature have investigated the presence of ocular abnormalities in neurofibromatosis type 1 (NF-1) patients. The aim of this study was to evaluate the prevalence of ocular abnormalities in a large population of NF1 patients, focusing on the choroidal changes.

The performance impairment (attentional blink, AB) on a second target (T2) when it is presented within 200-500 ms after a first target (T1) during rapid serial visual presentation (RSVP) is typically attributed to resource depletion. The AB does not occur when targets appear in immediate sequence (sparing). Recently, this account has been challenged by findings that the lag 1 sparing can spread to later lags when using a 3-target RSVP.

The allocation of attentional resources to a particular location or object in space involves two distinct processes: an orienting process and a focusing process. Indeed, it has been demonstrated that performance of different visual tasks can be improved when a cue, such as a dot, anticipates the position of the target (orienting), or when its dimensions (as in the case of a small square) inform about the size of the attentional window (focusing).

Eye charts are typically optimized to assess visual acuity (VA) with constant and controlled spacing, while close-to-acuity crowding limits letter identification in the normal fovea when adjacent letters are closely spaced. Here we developed a clinical tool that enables the assessment of acuity with different levels of crowding. In a cross-sectional study, we examined the developmental trajectories with our newly devised Milan Eye Chart (MEC).

Objective Here we evaluated the hypothesis that resting state electroencephalographic (EEG) cortical sources correlated with cognitive functions and discriminated asymptomatic treatment-naïve HIV subjects (no AIDS). Methods EEG, clinical, and neuropsychological data were collected in 103 treatment-naïve HIV subjects (88 males; mean age 39.8 years ± 1.1 standard error of the mean, SE). An age-matched group of 70 cognitively normal and HIV-negative (Healthy; 56 males; 39.0 years ± 2.0 SE) subjects, selected from a local university archive, was used for control purposes.

Objective: This study tested the hypothesis that markers of functional cortical source connectivity of resting
state eyes-closed electroencephalographic (rsEEG) rhythms may be abnormal in subjects with mild
cognitive impairment due to Alzheimer’s (ADMCI) and Parkinson’s (PDMCI) diseases compared to healthy
elderly subjects (Nold).
Methods: rsEEG data had been collected in ADMCI, PDMCI, and Nold subjects (N = 75 for any group).
eLORETA freeware estimated functional lagged linear connectivity (LLC) from rsEEG cortical sources.

OBJECTIVE:
This exploratory study provided a proof of concept of a new procedure using multivariate electroencephalographic (EEG) topographic markers of cortical connectivity to discriminate normal elderly (Nold) and Alzheimer's disease (AD) individuals.
METHOD: