Cortical sources of resting state electroencephalographic rhythms probe brain function in naïve HIV individuals
01 Pubblicazione su rivista
Babiloni Claudio, Noce Giuseppe, Pennica Alfredo, Onorati Paolo, Capotosto Paolo, Del Percio Claudio, Roma Paolo, Correr Valentina, Piccinni Elisa, Toma Ginevra, Soricelli Andrea, Di Campli Francesco, Gianserra Laura, Ciullini Lorenzo, Aceti Antonio, Teti Elisabetta, Sarmati Loredana, Crocetti Gloria, Ferri Raffaele, Catania Valentina, Pascarelli Maria Teresa, Andreoni Massimo, Ferracuti Stefano
ISSN: 1388-2457
Objective Here we evaluated the hypothesis that resting state electroencephalographic (EEG) cortical sources correlated with cognitive functions and discriminated asymptomatic treatment-naïve HIV subjects (no AIDS). Methods EEG, clinical, and neuropsychological data were collected in 103 treatment-naïve HIV subjects (88 males; mean age 39.8 years ± 1.1 standard error of the mean, SE). An age-matched group of 70 cognitively normal and HIV-negative (Healthy; 56 males; 39.0 years ± 2.0 SE) subjects, selected from a local university archive, was used for control purposes. LORETA freeware was used for EEG source estimation in fronto-central, temporal, and parieto-occipital regions of interest. Results Widespread sources of delta (