Ricerc@Sapienza

My research focuses on:

• regulation of innate immune response, with a focus on the role of chemotactic receptors in the migration and activation of immune cells.
• discovery and characterization of new chemokines and chemotactic receptors: we contributed to the characterization ChemR23 (Chemerin1), CCR6, and atypical receptors (ACKRs) such as ACKR2 and ACKR5, and CCRL2.
• biology of innate immune cells, with a focus on myeloid cells and their role in inflammation, autoimmunity and antitumor response.

The final goal is the identification of new therapeutic strategies to boost or restore antitumor immunity.