Our group has internationally recognized expertise in microbial genetics, bacterial genomics, computer science, and clinical microbiology as applied to the study of antibiotic resistance. At Sapienza, we have developed advanced expertise and instrumentation for bacterial genomics, and we have established methods to investigate the most relevant bacterial threats in nosocomial settings. In recent years, we have combined genomic approaches with innovative molecular methodologies to identify antimicrobial resistance mechanisms and to perform rapid molecular typing of resistant strains.