Cerebellar BDNF promotes exploration and seeking for novelty

01 Pubblicazione su rivista
Laricchiuta Daniela, Andolina Diego, Angelucci Francesco, Gelfo Francesca, Berretta Erica, Puglisi-Allegra Stefano, Petrosini Laura
ISSN: 1461-1457

Approach system considered a motivational system that activates reward-seeking behavior is associated with exploration/impulsivity, whereas avoidance system considered an attentional system that promotes inhibition of appetitive responses is associated with active overt withdrawal. Approach and avoidance dispositions are modulated by distinct neurochemical profiles and synaptic patterns. However, the precise working of neurons and trafficking of molecules in the brain activity predisposing to approach and avoidance are yet unclear.

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