Functionalized magnetic nanoparticles as catalysts for enantioselective Henry reaction
01 Pubblicazione su rivista
Sappino Carla, Primitivo Ludovica, De Angelis Martina, Oneto Domenici Marzia, Mastrodonato Andrea, Ben Romdan Ilaria, Tatangelo Chiara, Suber Lorenza, Pilloni Luciano, Ricelli Alessandra, Righi Giuliana
ISSN: 2470-1343
With the aim to easily recover and reuse the catalyst, an efficient amino alcohol catalyst previously tested in the asymmetric addition of diethylzinc to several aromatic aldehydes has been immobilized on proper functionalized superparamagnetic core−shell magnetite−silica nanoparticles and employed in the Henry reaction in the semi-homogeneous phase. The nanocatalyst exhibits a promising catalytic activity that remains unchanged in the three catalytic cycles performed. The results prove that highly efficient catalysts, by being immobilized on suitable magnetic nanosupports, can be easily recovered and reused, maintaining their catalytic behavior.