Exercise-induced epigenetic modifications for beneficial health manifestations
In the wake of multiple observations arising from diverse corners of physiological and molecular genetics, the onslaught of
epigenetic changes, gene x environment interaction, under current appearances requires rendition for purposes of displaying
both performance augmentation, amelioration of structural-functional impairment and the promotion of resilience manifested
by the lasting health benefits that arise from regular and consistent physical exercise. The notion that individuals, who
maintain an exercise habit that is pursued with regularity, incorporating appropriate combinations of endurance and
resistance, will present lower levels of “epigenetic ageing”, experience lesser metabolic disorders and express higher levels of
longevity. The relationships and outcomes of the exercise influences upon epigenetic mechanisms are viewed from several
angles, including: diet-exercise interactions, cognitive progression, maintenance and sustainability and cholinergic detriment
over the very young, young, mature and aged, i.e. the complete lifespan. Although the numerous health advantages granted
by regular physical exercise remain unequivocal it appears to be case that a plethora of the molecular and tissue adaptations
will confer heritable health implications, hopefully positive, for future generations.