Covid-19 and the role of smoking. The protocol of the multicentric prospective study COSMO-IT (COvid19 and SMOking in ITaly)

2020

ACTA BIOMEDICA

Covid-19 and the role of smoking. The protocol of the multicentric prospective study COSMO-IT (COvid19 and SMOking in ITaly)

01 Pubblicazione su rivista

Cattaruzza Maria Sofia, Gorini Giuseppe, Bosetti Cristina, Boffi Roberto, Lugo Alessandra, Veronese Chiara, Carreras Giulia, Santucci Claudia, Stival Chiara, Pacifici Roberta, Zagà Vincenzo, Gallus Silvano, Giulietti Federico, Sarzani Riccardo, Spannella Francesco, Del Donno Mario, Tartaglione Stefania, Marrazzo Giuseppina, Pelaia Girolamo, D'Agosto Vincenzo, Berti Alice, Voller Fabio, Cardellicchio Salvatore, Cresci Chiara, Foschino Barbaro Maria Pia, De Palma Raffaele, Negrini Simone, Sicbaldi Vera, Serafini Antonella, Bisconti Mario, Refolo Leonida, Landoni Giovanni, Rovere Patrizia, Veronesi Giulia, Faverio Paola, Garavello Werner, Pesci Alberto, Giacobbe Raffaella, Martucci Paola, Parrella Roberto, Scarano Francesco, Aiello Marina, Chetta Alfredo, Franco Cosimo, Mangia Angelo, Carrozzi Laura, Maggi Fabrizio, Monzani Fabio, Pistelli Francesco, Russo Patrizia, Sanna Antonio, Barreca Filippo Maria, Conti Valentina, Rossi Enrico, Ruli Mei, Ruli Silvana, Eslami Varzaneh Shokoofe, Principe Rosastella, Guerrini Simone, Sebastiani Alfredo, Galluccio Giovanni, Pezzuto Aldo, Ricci Alberto, Casali Elena, Mastroianni Claudio, Pirina Pietro, Polo Francesca, Beatrice Fabio, Romagnoli Micaela, Baraldo Massimo, Cojutti Pier Giorgio, Tascini Carlo, Pecori Davide, Graziano Elena, Tinghino Biagio

DOI: 10.23750/abm.v91i3.10373

ISSN: 2531-6745

The emergency caused by Covid-19 pandemic raised interest in studying lifestyles and comorbidities as important determinants of poor Covid-19 prognosis. Data on tobacco smoking, alcohol consumption and obesity are still limited, while no data are available on the role of e-cigarettes and heated tobacco products (HTP). To clarify the role of tobacco smoking and other lifestyle habits on COVID-19 severity and progression, we designed a longitudinal observational study titled COvid19 and SMOking in ITaly (COSMO-IT). About 30 Italian hospitals in North, Centre and South of Italy joined the study. Its main aims are: 1) to quantify the role of tobacco smoking and smoking cessation on the severity and progression of COVID-19 in hospitalized patients; 2) to compare smoking prevalence and severity of the disease in relation to smoking in hospitalized COVID-19 patients versus patients treated at home; 3) to quantify the association between other lifestyle factors, such as e-cigarette and HTP use, alcohol and obesity and the risk of unfavourable COVID-19 outcomes. Socio-demographic, lifestyle and medical history information will be gathered for around 3000 hospitalized and 700-1000 home-isolated, laboratory-confirmed, COVID-19 patients. Given the current absence of a vaccine against SARS-COV-2 and the lack of a specific treatment for -COVID-19, prevention strategies are of extreme importance. This project, designed to highly contribute to the international scientific debate on the role of avoidable lifestyle habits on COVID-19 severity, will provide valuable epidemiological data in order to support important recommendations to prevent COVID-19 incidence, progression and mortality.

prognosis Smoking tobacco