Ricerc@Sapienza

Hypertension is a major public health concern, considered the most prevalent among cardiovascular diseases, main cause of mortality and/or disability.
Over last years, the ultrasonic assessment of carotid intima-media thickness (c-IMT) has been used as a reliable, non-invasive diagnostic tool to evaluate presence of atherosclerosis and as a predictor of future CV events.
Based on the latest joint workshop of the European Federation of Periodontology and the World Heart Federation, there is a significant association between periodontal disease and cardiovascular diseases. The association between periodontitis and systemic conditions, such as diabetes, dyslipidaemia, hypertension and CVDs is well known, on the contrary, only a few authors have investigated the possible relationship between peri-implant diseases and systemic diseases.
The aims of this cross-sectional study are to report data on the possible association between IMT values and plaque presence and periodontitis and peri-implant diseases in hypertensive patients.
We designed a cross-sectional study, to conduct at the "Dpt of Translational and Precision Medicine" and "Dpt of Oral and Maxillo-Facial Sciences", "Sapienza" University of Rome, consecutively enrolling hypertensive patients, with at least one osseointegrated implant functioning for >5 years.
Each patient receives detailed descriptions of the study protocol, signing the inform consent form and give written approval to be included in the study population, according to the latest version of the World Medical Declaration of Helsinki (2013).
We consider: anamnestic evaluation, anthropometric and biochemical measurements, 24-hours ABPM, Carotid Doppler scan, screening for Metabolic Syndrome (MetS), Periodontal examination for definition of periodontitis [by computed Periodontal Screening and Recording (PSR), digital periapical x-rays, calibrated software].