Ricerc@Sapienza

Human papillomavirus (HPV) has been recognized as responsible of numerous neoplastic and preneoplastic disease in different anatomical district. Many researches have been conducted on these topic in these last few years, primarily in the field of gynecology but also in proctology, otorhinolaringoiatry, odontology, head and neck, dermatology and urology. Indeed many papers have been published also on the different diagnostic tools for HPV infection. Also the recent implementation of vaccines can change the history and the epidemiology of HPV related diseases.
Standing these premises the aim of these study is to approach the HPV infection in a multidisciplinary setting, with the objective to verify if a patient with a HPV lesion could present more HPV infections in different anatomical district and to give a comprehensive vision of the HPV disease to clinicians and patients. In particular, HPV genotyping represents an added value to assess whether positivity to HPV DNA in a second district is related to the primary HPV disease or it should be considered a different occurrence. The results of this study can be precious tools for the management of HPV patients in terms of epidemiology, treatment and prevention.