Ricerc@Sapienza

The research interest of our group is focused on the pathogenetic mechanisms involved in development and progression of solid tumors. Moreover, great attention has been paid to the development of new diagnostic tools for detection of genetic alterations addressable with targeted therapy. In the present research project we propose to investigate the following topics: 1) Role of MicroRNAs in pre-neoplastic lesions of the breast, and 2)Detection of ALK gene rearrangements in tumor tissue and in peripheral blood of patients with pulmonary adenocarcinoma: contribution of nanotechnologies,