Ricerc@Sapienza

Background.The term retinal detachment is used to describe a separation of the neurosensory retina from the retinal pigment epithelium (RPE). When the normal physiologic forces that maintain contact between the retina and the RPE (e.g., the metabolic pump of the RPE, the osmotic pressure of the choroid, and the more minor mechanical forces of the interphotoreceptor matrix) are compromised or overwhelmed, a retinal detachment occurs. Various pathologic conditions can upset the balance of the normal transretinal pressure gradient and result in subretinal fluid accumulation.
Purpose. Scleral buckling surgery and pars plana vitrectomy are competing methods in the treatment of retinal detachment. The recent development of spectral-domain optical coherence tomography (SD-OCT) has dramatically improved the visualization of retinal layer relative to conventional OCT, and offers new opportunities to investigate the discordances between anatomic and functional outcomes after retinal detachment surgery. Hence, the study aim is to use SD-OCT to compare the evaluation of Retinal Nerve Fiber Layer(RNFL), ganglion cell layer(GCL) and inner plexiform layer(IPL) between scleral buckling and vitrectomy for macular-off rhegmatogenous retinal detachment.
Methods. In this retrospective observational case series, we will evaluate all the patients who underwent scleral buckling surgery (group 1) and all the patients who underwent pars plana vitrectomy (group 2) as the primary surgery for macula-off rhegmatogenous retinal detachment. Spectral Domain Optical coherence Tomography(SD-OCT) was used to measure the retinal layers. 
Results.SD-OCT measurements were obtained 3 and 12¿months after the operation. All patients underwent pre- and postoperative best-corrected Visual Acuity (VA) testing [converted to the logarithm of the minimal angle of resolution (logMAR)], slit-lamp biomicroscopy, and dilated fundus examination.