The aim of our study is to assess the lower limb venous vessel thickness in patients with HIV and to link observed values to laboratory inflammatory and thrombophilia marker, in order to observe if HIV vasculitis may actually induce abnormalities also in venous vessel . Because of the increased incidence of venous involvement in HIV patients, and of the relative lack of clinical and phisiopathologic data o the subject in literature, a better understanding of hypercoagulability of HIV -infected patients is urgently needed ( Jackson 2019).
We propose a cross-sectional study . Routine laboratory tests for all patients and healthy controls, including complete blood count, fasting plasma glucose, and liver and renal function tests . Histories of traditional risk factors as hypertension ,hyperlipidaemia,and diabete mellitus will be recorded in n electronic data base. Thrombophilic risk factors or antiphospholipid antibodies will be screened.History of venous thrombosis or varicose veins will be an exclusion criteria.
Patients will be enrolled during the following 12 mounths from approvation of project from Ethical Committee.