The Effect of Poly (Glycerol Sebacate) Incorporation within Hybrid Chitin–Lignin Sol–Gel Nanofibrous Scaffolds

01 Pubblicazione su rivista
Abudula Tuerdimaimaiti, Gzara Lassaad, Simonetti Giovanna, Alshahrie Ahmed, Salah Numan, Morganti Pierfrancesco, Chianese Angelo, Fallahi Afsoon, Tamayol Ali, Bencherif Sidi, Adnan Memic.
ISSN: 1996-1944

Chitin and lignin primarily accumulate as bio-waste resulting from byproducts of
crustacean crusts and plant biomass. Recently, their use has been proposed for diverse and unique
bioengineering applications, amongst others. However, their weak mechanical properties need to be
improved in order to facilitate their industrial utilization. In this paper, we fabricated hybrid fibers
composed of a chitin–lignin (CL)-based sol–gel mixture and elastomeric poly (glycerol sebacate) (PGS)
using a standard electrospinning approach. Obtained results showed that PGS could be coherently
blended with the sol–gel mixture to form a nanofibrous scaffold exhibiting remarkable mechanical
performance and improved antibacterial and antifungal activity. The developed hybrid fibers showed
promising potential in advanced biomedical applications such as wound care products. Ultimately,
recycling these sustainable biopolymers and other bio-wastes alike could propel a “greener” economy

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