Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum
04 Pubblicazione in atti di convegno
Denzi Agnese, Hanna Hanna, Andre Franck M., Mir Lluis M., Apollonio Francesca, Liberti Micaela
Microsecond pulsed electric fields (?sPEFs) with amplitude of tens of kV/m are used to permeabilize the plasma membrane whereas nanosecond pulsed electric fields of MV/m also permeabilize cell internal structures, such as the endoplasmic reticulum. In this work, a numerical realistic model of cell and its reticulum has been realized to study the use of ?sPEFs also for the permeabilization of this internal structure