Compulsive addiction-like aggressive behavior in mice

01 Pubblicazione su rivista
Golden Sam A, Heins Conor, Venniro Marco, Caprioli Daniele, Zhang Michelle, Epstein David H, Shaham Yavin
ISSN: 0006-3223

Some people are highly motivated to seek aggressive encounters, and among those who have been incarcerated for such behavior, recidivism rates are high. These observations echo two core features of drug addiction: high motivation to seek addictive substances, despite adverse consequences, and high relapse rates. Here we used established rodent models of drug addiction to determine whether they would be sensitive to "addiction-like" features of aggression in CD-1 mice.

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