Diagnostic performance of PET/MR in the evaluation of active inflammation in Crohn disease
01 Pubblicazione su rivista
Catalano Onofrio Antonio, Wu Vincent, Mahmood Umar, Signore Alberto, Vangel Mark, Soricelli Andrea, Salvatore Marco, Gervais Debra, Rosen Bruce R
ISSN: 2160-8407
This study investigates the performance of PET/MR versus each sub-modality alone in the assessment of active inflammation in patients with Crohn disease, when compared to surgery as standard of reference. Sensitivity for detecting active inflammation was 91.5% for PET, 80% for MR, and 88% for PET/MR. Specificity for active inflammation was 74% for PET, 87% for MR, and 93% for PET/MR. Diagnostic accuracy was 84% for PET, 83% for MR, and 91% for PET/MR. In conclusion, PET/MR is significantly more accurate than either sub-modality alone and more specific than PET alone in the detection of active inflammation in patients with Crohn disease.