Soluble CD163 and mannose receptor as markers of liver disease severity and prognosis in patients with primary biliary cholangitis
01 Pubblicazione su rivista
Bossen Lars, Rebora Paola, Bernuzzi Francesca, Jepsen Peter, Gerussi Alessio, Andreone Pietro, Galli Andrea, Terziroli Benedetta, Alvaro Domenico, Labbadia Giancarlo, Aloise Chiara, Baiocchi Leonardo, Giannini Edoardo, Abenavoli Ludovico, Toniutto Pierluigi, Marra Fabio, Marzioni Marco, Niro Grazia, Floreani Annarosa, Møller Holger J, Valsecchi Maria G, Carbone Marco, Grønbaek Henning, Invernizzi Pietro
DOI: 10.1111/liv.14466
ISSN: 1478-3223
In primary biliary cholangitis (PBC), macrophages are involved in liver inflammation and fibrosis. The macrophage activation markers, soluble (s)CD163 and mannose receptor (sMR) are associated with liver disease severity and prognosis in other chronic liver diseases. We aimed to investigate sCD163 and sMR in patients with PBC.