A Specific Urinary Amino Acid Profile Characterizes People with Kidney Stones
01 Pubblicazione su rivista
Primiano Aniello, Persichilli Silvia, Ferraro Pietro Manuel, Calvani Riccardo, Biancolillo Alessandra, Marini Federico, Picca Anna, Marzetti Emanuele, Urbani Andrea, Gervasoni Jacopo
DOI: 10.1155/2020/8848225
ISSN: 0278-0240
Urolithiasis is the process of stone formation in the urinary tract. Its etiology is only partly known, and efficient therapeutic approaches are currently lacking. Metabolomics is increasingly used in biomarkers discovery for its ability to identify mediators of relevant (patho)physiological processes. Amino acids may be involved in kidney stone formation. The aim of the present study was to investigate the presence of an amino acid signature in stone former urine through a targeted metabolomic approach.