Antonella Di Sotto

Pubblicazioni

Titolo Pubblicato in Anno
A polyphenol rich extract from Solanum melongena L. DR2 peel exhibits antioxidant properties and anti-herpes simplex virus type 1 activity in vitro MOLECULES 2018
Chemosensitizing effects of beta-caryophyllene oxide in liver cancer JOURNAL OF HEPATOLOGY 2018
The natural sesquiterpene β- caryophyllene acts as an enviromental decontaminant through the interference with the STAT3 signalling pathway 2018
Chromatographic analyses, in vitro biological activities, and cytotoxicity of Cannabis sativa L. essential oil: a multidisciplinary study MOLECULES 2018
SPC liposomes as possible delivery systems for improving bioavailability of the natural sesquiterpene β-caryophyllene: lamellarity and drug-loading as key features for a rational drug delivery design PHARMACEUTICS 2018
Chemosensitizing properties of β-caryophyllene and β-caryophyllene oxide in combination with doxorubicin in human cancer cells ANTICANCER RESEARCH 2017
Genotoxicity assessment of piperitenone oxide: an in vitro and in silico evaluation FOOD AND CHEMICAL TOXICOLOGY 2017
Phytochemical analysis and effects on ingestive behaviour of a caralluma fimbriata extract FOOD AND CHEMICAL TOXICOLOGY 2017
β-caryophyllene and low-doses of doxorubicin against liver cancer cells: a “metronomic chemotherapy” Italian Journal of Anatomy and EmbryologyITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY 2017
Antiviral and antioxidant activity of a hydroalcoholic extract from Humulus lupulus L. Atti del Convegno 2017
β-Caryophyllene oxide as a new chemosensitizing agent to enhance sorafenib efficacy in liver cancer chemotherapy. Atti del Convegno 2017
Effects of the metronomic treatment of β-caryophyllene in combination with lowdose doxorubicin in liver cancer cells. Atti del Convegno 2017
Natural sesquiterpenes as potential modulator of intracellular pathways in CCA proliferation EUROPEAN JOURNAL OF HISTOCHEMISTRY 2017
Mutagenicity of cigarette butt waste in the bacterial reverse mutation assay: The protective effects of β-caryophyllene and β-caryophyllene oxide ENVIRONMENTAL TOXICOLOGY 2016
Letter to the editor regarding “RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-7” by Api et al., 2015 FOOD AND CHEMICAL TOXICOLOGY 2016
New insights in oxybutynin chemical stability: identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 2016
Sisymbrium officinale (L.) Scop. and its polyphenolic fractions inhibit the mutagenicity of tert-butylhydroperoxide in Escherichia coli WP2uvrAR strain PHYTOTHERAPY RESEARCH 2016
α-Hexylcinnamaldehyde synergistically increases doxorubicin cytotoxicity towards human cancer cell lines ANTICANCER RESEARCH 2016
Chemopreventive effects of β-caryophyllene against cigarette smoke damage in upper airway cells --- 2016
Interaction of β-caryophyllene and β-caryophyllene oxide with phospholipid bilayers: differential scanning calorimetry study THERMOCHIMICA ACTA 2015

ERC

  • LS7_7

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Basic research in pharmacology and toxicology of natural substances and herbal products

- Genoprotective properties of natural compounds (especially terpenes, flavonoids and glucosinolates) towards environmental pollutants and the mechanisms involved.

- Chemopreventive and chemosensitizing effects of caryophyllane sesquiterpenes

- Nutraceutical studies on food and waste

- Genotoxicity studies of natural products

- In vivo effects of of natural products on liver function

Keywords

medicinal plants
Cancer chemoprevention and therapy
ethnopharmacology and nutraceutics
Modulation of Oxidative Stress
environmental pollutants
beta-caryophyllene
caryophyllane sesquiterpenes
hyperglycemia-induced oxidative stress
Chemosensitizing agents
Triple negative breast cancer
chemoresistance
genotoxicity assessment
genoprotection

Progetti di Ricerca

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