Antonella Di Sotto

Pubblicazioni

Titolo Pubblicato in Anno
Chemosensitizing properties of ß-caryophyllene oxide in hepatocellular carcinoma GA – 69th Annual Meeting eBook of Abstracts 2021
Interaction of limonene, terpineol, and 1,8 cineol with a model of biomembrane: A DSC study THERMOCHIMICA ACTA 2021
Role of caryophyllane sesquiterpenes in the entourage effect of felina 32 Hemp inflorescence phytocomplex in triple negative MDA-MB-468 breast cancer cells MOLECULES 2021
Phytochemical and biological characterization of Italian “sedano bianco di Sperlonga” protected geographical indication celery ecotype. A multimethodological approach FOOD CHEMISTRY 2020
Potentiation of low-dose doxorubicin cytotoxicity by affecting p-glycoprotein through caryophyllane sesquiterpenes in hepg2 cells: an in vitro and in silico study INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Cannabis sativa L. inflorescences from monoecious cultivars grown in central Italy: an untargeted chemical characterization from early flowering to ripening MOLECULES 2020
Modulation of STAT3 signaling, cell redox defenses and cell cycle checkpoints by β-caryophyllene in cholangiocarcinoma cells: possible mechanisms accounting for doxorubicin chemosensitization and chemoprevention CELLS 2020
Antiarthritic effects of a root extract from harpagophytum procumbens dc: novel insights into the molecular mechanisms and possible bioactive phytochemicals NUTRIENTS 2020
Plant-derived nutraceuticals and immune system modulation: an evidence-based overview VACCINES 2020
Commercial hemp seed oils: a multimethodological characterization APPLIED SCIENCES 2020
Chemico-biological characterization of Torpedino Di Fondi® tomato fruits. A comparison with San Marzano cultivar at two ripeness stages ANTIOXIDANTS 2020
Chemopreventive potential of caryophyllane sesquiterpenes: an overview of preliminary evidence CANCERS 2020
β-hexachlorocyclohexane: a small molecule with a big impact on human cellular biochemistry BIOMEDICINES 2020
Correlation between the antimicrobial activity and metabolic profiles of cell free supernatants and membrane vesicles produced by lactobacillus reuteri DSM 17938 MICROORGANISMS 2020
Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps ARCHIVES OF TOXICOLOGY 2019
Caryophyllane sesquiterpenes reverse sorafenib-chemoresistance through Pgp and STAT3 pathways in liver cancer cells. 2019
Studying the chemopreventive properties of inflorescences from industrial hemp variety Felina 32 in relation to the phenolic and terpenoid composition 2019
Hypoglycemic, antiglycation, and cytoprotective properties of a phenol-rich extract from waste peel of punica granatum L. Var. Dente di cavallo DC2 MOLECULES 2019
Caryophyllane sesquiterpenes inhibit dna-damage by tobacco smoke in bacterial and mammalian cells FOOD AND CHEMICAL TOXICOLOGY 2018
Capsicum annuum L. var. Cornetto di Pontecorvo PDO. Polyphenolic profile and in vitro biological activities JOURNAL OF FUNCTIONAL FOODS 2018

ERC

  • LS7_7

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Basic research in pharmacology and toxicology of natural substances and herbal products

- Genoprotective properties of natural compounds (especially terpenes, flavonoids and glucosinolates) towards environmental pollutants and the mechanisms involved.

- Chemopreventive and chemosensitizing effects of caryophyllane sesquiterpenes

- Nutraceutical studies on food and waste

- Genotoxicity studies of natural products

- In vivo effects of of natural products on liver function

Keywords

medicinal plants
Cancer chemoprevention and therapy
ethnopharmacology and nutraceutics
Modulation of Oxidative Stress
environmental pollutants
beta-caryophyllene
caryophyllane sesquiterpenes
hyperglycemia-induced oxidative stress
Chemosensitizing agents
Triple negative breast cancer
chemoresistance
genotoxicity assessment
genoprotection

Progetti di Ricerca

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