Antonio Franchitto | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Differential impact of MT1 and MT2 melatonin receptor deletion on biliary proliferation, senescence, and liver fibrosis during cholestatic liver injury	HEPATOLOGY	2017
Secretin receptor antagonist treatment reduces biliary damage and liver fibrosis in a mouse model of early stage primary biliary cholangitis (PBC), but not advanced PBC	HEPATOLOGYHEPATOLOGY	2017
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles	CELL REPORTS	2017
Progenitor cell niches in the human pancreatic duct system and associated pancreatic duct glands: an anatomical and immunophenotyping study	JOURNAL OF ANATOMY	2016
Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration	STEM CELLS INTERNATIONAL	2016
The secretin/secretin receptor axis modulates liver fibrosis through changes in TGF-β1 biliary secretion	HEPATOLOGY	2016
Macrophage activation in pediatric nonalcoholic fatty liver disease (NAFLD) correlates with hepatic progenitor cell response via Wnt3a pathway	PLOS ONE	2016
Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease	LABORATORY INVESTIGATION	2016
MiR-200b modulates angiogenesis and liver fibrosis in the Mdr2-/- model of primary sclerosing cholangitis	GastroenterologyGASTROENTEROLOGY	2016
Gonadotropin-releasing hormone (GnRH) contributes to liver fibrosis in primary sclerosing cholangitis (PSC) through enhanced epithelial-mesenchymal transition (EMT) in small but increased senescence in large cholangiocytes	HEPATOLOGY	2016
Inhibition of the substance P/neurokinin-1 receptor (NK-1R) axis decreases liver fibrosis in the Mdr2(-/-) mouse model of primary sclerosing cholangitis (PSC) through changes in senescence in cholangiocytes and hepatic stellate cells	HEPATOLOGY	2016
Melatonin Therapy Reduces Biliary Proliferation and Hepatic Fibrosis in the Mdr2(-/-) Mouse Model of Primary Sclerosing Cholangitis (PSC) By Decreased Expression of miR-200b and Angiogenic Factors	GASTROENTEROLOGY	2016
Profiles of cancer stem cell subpopulations in cholangiocarcinomas	THE AMERICAN JOURNAL OF PATHOLOGY	2015
IMMUNOLOCALIZATION OF COCAINE-AMPHETAMINE REGULATED TRANSCRIPT (CART) IN BILIARY EPITHELIUM	EUROPEAN JOURNAL OF HISTOCHEMISTRY	2015
Ischemia reperfusion of the hepatic artery induces the functional damage of large bile ducts by changes in the expression of angiogenic factors	AMERICAN JOURNAL OF PHYSIOLOGY: GASTROINTESTINAL AND LIVER PHYSIOLOGY	2015
Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms	THE AMERICAN JOURNAL OF PATHOLOGY	2015
Knockdown of the melatonin receptor, MT1, reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated (BDL) mice	HEPATOLOGYHEPATOLOGY	2015
Down-regulation of the secretin/SR (SCT/SR) axis is coupled with functional biliary damage in dnTGF beta RII mice and human primary biliary cirrhosis (PBC)	HEPATOLOGYHEPATOLOGY	2015
Knockout of the secretin/secretin receptor axis delays regeneration of small and large cholangiocytes by enhanced senescence following 70\% partial hepatectomy (PH)	HEPATOLOGYHEPATOLOGY	2015
FEASIBLE TRANSPLANTATION OF HUMAN FETAL BILIARY TREE STEM/PROGENITOR CELLS IN PATIENTS WITH ADVANCED LIVER CIRRHOSIS	DIGESTIVE AND LIVER DISEASE	2015

Progetti di Ricerca

Role and activation mechanisms of Biliary and hepatic stem/progenitor cells during liver and biliary diseases.
Ruolo dell'antagonista del recettore della secretina nel danno delle vie biliari e della fibrosi epatica in modello sperimentale di colangite biliare primitiva.