Carla Cicchini


Titolo Pubblicato in Anno
Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity CELL DEATH & DISEASE 2023
SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Exosome-Associated circRNAs as Key Regulators of EMT in Cancer CELLS 2022
Design and functional validation of a mutant variant of the lncRNA HOTAIR to counteract Snail function in Epithelial-to-Mesenchymal Transition CANCER RESEARCH 2020
YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation CELL DEATH & DISEASE 2019
Genetica: un approccio molecolare (V edizione) 2019
A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets NATURE COMMUNICATIONS 2018
The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter ONCOTARGET 2018
The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation CELL DEATH AND DIFFERENTIATION 2018
Exosome-Mediated Signaling in Epithelial to Mesenchymal Transition and Tumor Progression JOURNAL OF CLINICAL MEDICINE 2018
Functional Roles and Therapeutic Applications of Exosomes in Hepatocellular Carcinoma BIOMED RESEARCH INTERNATIONAL 2017
Targeting of polycombs to DNA in EMT ONCOTARGET 2017
The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition ONCOGENE 2017
Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes STEM CELLS INTERNATIONAL 2016
Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis STEM CELLS INTERNATIONAL 2016
The lncRNA HOTAIR links the repressor Snail to epigenetic modifications of specific genomic sites in Epithelial-to-Mesenchymal Transition FISV - Federazione Italiana Scienze della Vita Program and Abstracts of the XIV FISV CONGRESS 2016
The RNA binding protein SYNCRIP controls microRNAs sorting in exosomes FISV - Federazione Italiana Scienze della Vita Program and Abstracts of the XIV FISV CONGRESS 2016
The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting CELL REPORTS 2016
SETDB1 is a new promising target in HCC therapy CHINESE CLINICAL ONCOLOGY 2016
Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte LIVER INTERNATIONAL 2015


  • LS2_3
  • LS3_5
  • LS3_9
  • LS4_12


  • Life-science technologies & biotechnologies

Interessi di ricerca

Research activity mainly focused on genetic and epigenetic molecular mechanisms controlling i) the epithelial-to-mesenchymal transition (EMT)-mesenchymal-to-epithelial transition (MET) dynamics in physiology and pathology; ii) the intercellular communication mediated by extracellular vesicles (EVs).


EMT Epithelial-Mesenchymal Transition
hepatocyte nuclear factor 4 alpha (HNF4α)
RNA binding proteins
cancer-derived exosomes

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