Claudio Di Cristofano


Titolo Pubblicato in Anno
Incidental papillary thyroid microcarcinoma in consecutive patients undergoing thyroid surgery for benign disease. A single center experience ANNALI ITALIANI DI CHIRURGIA 2023
Neuropeptide Y promotes human M2 macrophage polarization and enhances p62/SQSTM1-dependent autophagy and NRF2 activation INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Incidental parathyroidectomy during total thyroidectomy as a possible risk factor of hypocalcemia. Experience of a single center and review of literature ACTA ENDOCRINOLOGICA 2021
Expression of TGR5 in adipose tissue in relation to metabolic impairment and adipose tissue dysfunction in human obesity METABOLISM AND TARGET ORGAN DAMAGE 2021
Predictive markers of long-term recurrence in chronic rhinosinusitis with nasal polyps AMERICAN JOURNAL OF OTOLARYNGOLOGY 2020
Non-antibiotic prophylaxis in thyroid surgery. Experience of a single Institution and revision of literature ANNALI ITALIANI DI CHIRURGIA 2020
A case of hidradenitis suppurativa successfully treated with apremilast in a patient with psoriasis and SAMPUS DERMATOLOGIC THERAPY 2020
A late onset widespread skin rash in a previous Covid-19 infected patient. Viral or multidrug effect? JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 2020
Relationship Between Hepatic and Systemic Angiopoietin-Like 3, Hepatic Vitamin D Receptor Expression and NAFLD in Obesity LIVER INTERNATIONAL 2020
Melanoma. Double BRAF mutation, double chance to treat? DERMATOLOGIC THERAPY 2020
PET-guided switch from immunotherapy to targeted therapy in a metastatic melanoma patients. A personalized approach LA CLINICA TERAPEUTICA 2020
Immunohistochemical detection of IL-17 and IL-23 improves the identification of patients with a possible diagnosis of Sjogren's syndrome PATHOLOGY RESEARCH AND PRACTICE 2020
Circulating dipeptidyl peptidase-4 is independently associated with the presence and severity of NAFLD/NASH in individuals with and without obesity and metabolic disease JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 2020
A rare case of omental extra-gastrointestinal stromal tumor showing two coexisting mutations on exon 14 of the PDGFRA gene GASTROENTEROLOGY REPORT 2020
Adipose tissue remodelling in obese subjects is a determinant of presence and severity of fatty liver disease DIABETES/METABOLISM RESEARCH AND REVIEWS 2020
Reduced biliverdin reductase-a expression in visceral adipose tissue is associated with adipocyte dysfunction and nafld in human obesity INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Angiopoietin-like protein 4 overexpression in visceral adipose tissue from obese subjects with impaired glucose metabolism and relationship with lipoprotein lipase INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020
Granzyme B Expression in Visceral Adipose Tissue Associates With Local Inflammation and Glyco-Metabolic Alterations in Obesity FRONTIERS IN IMMUNOLOGY 2020
Genetic lesions disrupting calreticulin 3′-untranslated region in JAK2 mutation-negative polycythemia vera AMERICAN JOURNAL OF HEMATOLOGY 2020
Relationship between hepatic and systemic angiopoietin-like 3, hepatic Vitamin D receptor expression and NAFLD in obesity LIVER INTERNATIONAL 2020


  • LS4_12


  • Life-science technologies & biotechnologies

Interessi di ricerca

L'attività di ricerca del Dr. Di Cristofano è prevalentemente dedicata allo studio dei meccanismi molecolari associati alla carcinogenesi ed alla progressione neoplastica ed all individuazione di eventuali bersagli terapeutici nei tumori solidi utilizzando metodiche di biologia molecolare per l analisi delle alterazioni del genoma e di espressione genica nelle cellule e nei campioni tissutali. Un altro filone rilevante di ricerca è quello delle indagini sulle interazioni ed il traffico nucleocitoplasmatico delle proteine mediante la loro localizzazione subcellulare e co-localizzazione con metodiche immunoistochimiche nelle cellule e nei tessuti. In tali ambiti, in dipendenza anche della propria attività clinica di anatomo-patologo, il Dr. Di Cristofano ha focalizzato il suo interesse nella patologia neoplastica del rene, della mammella, dei tessuti molli e della utilizzando in particolare metodiche quali la microdissezione laser (LCM), l ibridazione in situ fluorescente (FISH) e i microarray tissutali (TMA) per gli studi di patologia molecolare.


Adult cancer
biomolecular analysis

Laboratori di ricerca

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma