Laura Amicone

Pubblicazioni

Titolo Pubblicato in Anno
Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity CELL DEATH & DISEASE 2023
Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity CELL DEATH & DISEASE 2023
The lncRNA HOTAIR: a pleiotropic regulator of epithelial cell plasticity JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 2023
Geoffrey Cooper LA CELLULA 2023
SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Exosome-Associated circRNAs as Key Regulators of EMT in Cancer CELLS 2022
TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases FRONTIERS IN PHARMACOLOGY 2019
YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation CELL DEATH & DISEASE 2019
Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY 2018
The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition ONCOGENE 2017
The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition ONCOGENE 2017
Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes STEM CELLS INTERNATIONAL 2016
Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis STEM CELLS INTERNATIONAL 2016
TGFbeta induces binucleation/polyploidization in hepatocytes through a src-Dependent cytokinesis failure PLOS ONE 2016
Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte LIVER INTERNATIONAL 2015
Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29 BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS 2015
A lncRNA-mediated interaction between Snail and Ezh2 governs epigenetic modifications causal to EMT of the hepatocyte 2015
A lncRNA-mediated interaction between Snail and Ezh2 governs epigenetic modifications causal to EMT of the hepatocyte ABCD congress 2015, The biennial congress of italian association of cell biology and differentiation 2015
A lncRNA-mediated interaction between Snail and Ezh2 governs epigenetic modifications causal to EMT of the hepatocyte 2015
Epigenetic Regulation in Hepatocellular Carcinoma Requires Long Noncoding RNAs BIOMED RESEARCH INTERNATIONAL 2015

ERC

  • LS1_9
  • LS2_4
  • LS4_12

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

-Study of niche factors and molecular mechanisms controlling liver stem cell biology (differentiation and maitenance). 
-Study of the mechanisms controlling the epithelial to mesenchymal transition.
-Study of the role of the mechano-transducer YAP  in hepatocyte differentiation and in hepatocarcinoma.

Keywords

Hepatocyte differentiation
hepatocyte nuclear factor 4 alpha (HNF4α)
cell signaling
Cell lines
gene expression analysis

Progetti di Ricerca

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