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sergio.fucile@uniroma1.it
Sergio Fucile
Professore Ordinario
Struttura:
DIPARTIMENTO DI FISIOLOGIA E FARMACOLOGIA "VITTORIO ERSPAMER"
E-mail:
sergio.fucile@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype
JOURNAL OF MEDICINAL CHEMISTRY
2020
Chronic neural interfacing with cerebral cortex using single-walled carbon nanotube-polymer grids
JOURNAL OF NEURAL ENGINEERING
2020
Calcium influx through muscle nAChR-channels: one route, multiple roles
NEUROSCIENCE
2019
Silicon nanowires to detect electric signals from living cells
MATERIALS RESEARCH EXPRESS
2019
Extracellular mild acidosis decreases the Ca2+ permeability of the human NMDA receptors
CELL CALCIUM
2019
Silicon nanowires as biocompatibile electronics-biology interface
INTERNATIONAL SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS CONFERENCE
2019
Biocompatibility of silicon nanowires: A step towards IC detectors
AIP CONFERENCE PROCEEDINGS
2019
Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors
FASEB JOURNAL
2019
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
CELL COMMUNICATION AND SIGNALING
2019
Novel N-aryl nicotinamide derivatives: Taking stock on 3,6-diazabicyclo[3.1.1]heptanes as ligands for neuronal acetylcholine receptors
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2019
Loss of constitutive functional gamma-aminobutyric acid type A-B receptor crosstalk in layer 5 pyramidal neurons of human epileptic temporal cortex
EPILEPSIA
2018
Pyridinyl- and pyridazinyl-3,6-diazabicyclo[3.1.1]heptane-anilines: Novel selective ligands with subnanomolar affinity for α4β2nACh receptors
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2018
The fifth subunit in α3β4 nicotinic receptor is more than an accessory subunit
THE FASEB JOURNAL
2018
From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2017
LAV-BPIFB4 isoform modulates eNOS signaling through Ca2+/PKC-alpha dependent mechanism
CARDIOVASCULAR RESEARCH
2017
The distribution of charged amino acid residues and the Ca(2+) permeability of nicotinic acetylcholine receptors: a predictive model
FRONTIERS IN MOLECULAR NEUROSCIENCE
2017
Expression of the K(+)/Cl(-) cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors
NEUROPHARMACOLOGY
2016
Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
2016
Le tecniche teatrali sono in grado di influenzare positivamente il cervello umano?
BIBLIOTECA TEATRALE
2016
Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neurons
THE FASEB JOURNAL
2015
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Progetti di Ricerca
Il controllo della concentrazione di Ca2+ libero intracellulare per la riduzione del danno cellulare da eccitotossicità
Positive allosteric modulation of human neuronal nicotinic acetylcholine receptors as a new strategy to enhance cortical GABAergic inhibitory neurotransmission and treat epilepsy
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