Sergio Fucile

Pubblicazioni

Titolo	Pubblicato in	Anno
α4β2* nicotinic acetylcholine receptors drive human temporal glutamate/GABA balance toward inhibition	THE JOURNAL OF PHYSIOLOGY	2025
Selective Reduction of Ca2+ Entry Through the Human NMDA Receptor: a Quantitative Study by Simultaneous Ca2+ and Na+ Imaging	MOLECULAR NEUROBIOLOGY	2024
Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties	HELIYON	2024
Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase, modulates glycosphingolipid metabolism and results therapeutically effective in experimental models of Huntington's disease	MOLECULAR THERAPY	2023
Natural killer cells and innate lymphoid cells 1 tune anxiety-like behavior and memory in mice via interferon-γ and acetylcholine	NATURE COMMUNICATIONS	2023
α7 Nicotinic Acetylcholine Receptors May Improve Schwann Cell Regenerating Potential via Metabotropic Signaling Pathways	CELLS	2023
Common and Rare Variants in TMEM175 Gene Concur to the Pathogenesis of Parkinson's Disease in Italian Patients	MOLECULAR NEUROBIOLOGY	2023
Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase, modulates glycosphingolipid metabolism and results therapeutically effective in experimental models of Huntington's disease	MOLECULAR THERAPY	2023
Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3	FRONTIERS IN MOLECULAR NEUROSCIENCE	2023
Contribution of CACNA1H Variants in Autism Spectrum Disorder Susceptibility	FRONTIERS IN PSYCHIATRY	2022
Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity	BIOMEDICINES	2022
A Progressive Build-up of Perineuronal Nets in the Somatosensory Cortex Is Associated with the Development of Chronic Pain in Mice	THE JOURNAL OF NEUROSCIENCE	2022
5-HT3 Receptors in Rat Dorsal Root Ganglion Neurons: Ca2+ Entry and Modulation of Neurotransmitter Release	LIFE	2022
ATP-evoked intracellular Ca2+ transients shape the ionic permeability of human microglia from epileptic temporal cortex	JOURNAL OF NEUROINFLAMMATION	2021
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9-nicotinic ligands on glioblastoma cells	PHARMACOLOGICAL RESEARCH	2021
New nutraceutical combination reduces blood pressure and improves exercise capacity in hypertensive patients via a nitric oxide-dependent mechanism	JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE	2020
Co-occurring WARS2 and CHRNA6 mutations in a child with a severe form of infantile parkinsonism	PARKINSONISM & RELATED DISORDERS	2020
Modulation of GABAergic dysfunction due to SCN1A mutation linked to Hippocampal Sclerosis	ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY	2020
The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia	SCHIZOPHRENIA BULLETIN	2020
Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype	JOURNAL OF MEDICINAL CHEMISTRY	2020

Ricerc@Sapienza

Pubblicazioni

Progetti di Ricerca

Laboratori di ricerca