Annarita Fiorillo | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Study of manganese binding to the ferroxidase centre of human H-type ferritin	JOURNAL OF INORGANIC BIOCHEMISTRY	2018
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme	PLOS ONE	2018
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors	MOLECULAR PHARMACEUTICS	2018
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents	CANCER DRUG RESISTANCE	2018
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives	JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY	2017
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2017
Binding of doxorubicin to sorcin impairs cell death and increases drug resistance in cancer cells	CELL DEATH & DISEASE	2017
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure?	AMINO ACIDS	2017
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis	FUTURE MEDICINAL CHEMISTRY	2017
Short peptides from leucyl-tRNA synthetase rescue disease-causing mitochondrial tRNA point mutations	HUMAN MOLECULAR GENETICS	2016
Structural basis of Sorcin-mediated calcium-dependent signal transduction	SCIENTIFIC REPORTS	2015
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking	SCIENTIFIC REPORTS	2015
Targeting polyamine metabolism for finding new drugs against leishmaniasis: a review	MINI-REVIEWS IN MEDICINAL CHEMISTRY	2015
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions	JOURNAL OF CHEMICAL INFORMATION AND MODELING	2015

Progetti di Ricerca

Development of broad-spectrum trypanocidal agents through target-based drug discovery