Maria Saveria Gilardini Montani

Pubblicazioni

Titolo	Pubblicato in	Anno
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells	BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS	2022
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation	CARCINOGENESIS	2022
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway	BIOMEDICINES	2022
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Mechanisms of Sensitivity and Resistance of Primary Effusion Lymphoma to Dimethyl Fumarate (DMF)	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress	CELL DEATH DISCOVERY	2022
Ire1 alpha/xbp1 axis sustains primary effusion lymphoma cell survival by promoting cytokine release and stat3 activation	BIOMEDICINES	2021
P53‐r273h sustains ros, pro‐inflammatory cytokine release and mtor activation while reducing autophagy, mitophagy and ucp2 expression, effects prevented by wtp53	BIOMOLECULES	2021
P62/sqstm1/keap1/nrf2 axis reduces cancer cells death-sensitivity in response to zn(Ii)–curcumin complex	BIOMOLECULES	2021
The cross-talk between STAT1/STAT3 and ROS up-regulates PD-L1 and promotes the release of pro-inflammatory/immune suppressive cytokines in primary monocytes infected by HHV-6B	VIRUS RESEARCH	2021
PGE2 released by pancreatic cancer cells undergoing ER stress transfers the stress to DCs impairing their immune function	MOLECULAR CANCER THERAPEUTICS	2021
Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment	BIOMEDICINES	2021
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53	EXPERIMENTAL CELL RESEARCH	2021
New insights into curcumin-and resveratrol-mediated anti-cancer effects	PHARMACEUTICALS	2021
Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross-talk with p53 to activate p21	IUBMB LIFE	2021
HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease	BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE	2020
Interplay between endoplasmic reticulum (ER) stress and autophagy induces mutant p53H273 degradation	BIOMOLECULES	2020
PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR	BIOMOLECULES	2020
KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression	BRITISH JOURNAL OF CANCER	2020
A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2020

ERC

LS1_2
LS1_9
LS4_12
LS6
LS6_8

Interessi di ricerca

Risposta immunitaria all'infezione da virus erpetici. Cancerogenesi virale e nuove terapie anti-cancro.

Keywords

Herpesvirus 4

innate immune cells

aggressive cancer

cell death