Maria Saveria Gilardini Montani

Pubblicazioni

Titolo	Pubblicato in	Anno
KSHV dysregulates bulk macroautophagy, mitophagy and UPR to promote endothelial to mesenchymal transition and CCL2 release, key events in viral-driven sarcomagenesis	INTERNATIONAL JOURNAL OF CANCER	2020
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway	FRONTIERS IN ONCOLOGY	2020
Viral Infection and Autophagy Dysregulation: The Case of HHV-6, EBV and KSHV	CELLS	2020
EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation	AUTOPHAGY	2019
Impact of HHV-6A and HHV-6B lytic infection on autophagy and endoplasmic reticulum stress	JOURNAL OF GENERAL VIROLOGY	2019
Mutant p53, stabilized by its interplay with HSP90, activates a positive feed-back loop between NRF2 and p62 that induces chemio-resistance to Apigenin in pancreatic cancer cells	CANCERS	2019
Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response	ONCOTARGET	2019
Kaposi Sarcoma Herpes Virus (KSHV) infection inhibits macrophage formation and survival by counteracting Macrophage Colony-Stimulating Factor (M-CSF)-induced increase of Reactive Oxygen Species (ROS), c-Jun N-terminal kinase (JNK) phosphorylation and autophagy	THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY	2019
Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2019
HHV-6B reduces autophagy and induces ER stress in primary monocytes impairing their survival and differentiation into dendritic cells	VIRUS RESEARCH	2019
Quercetin interrupts the positive feedback loop between STAT3 and IL-6, promotes autophagy, and reduces ROS, preventing EBV-driven B cell immortalization	BIOMOLECULES	2019
EBV up-regulates PD-L1 on the surface of primary monocytes by increasing ROS and activating TLR signaling and STAT3	JOURNAL OF LEUKOCYTE BIOLOGY	2018
Cytotoxic drugs activate KSHV lytic cycle in latently infected PEL cells by inducing a moderate ROS increase controlled by HSF1, NRF2 and p62/SQSTM1	VIRUSES	2018
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways	JOURNAL OF NUTRITIONAL BIOCHEMISTRY	2017
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells	CELLULAR ONCOLOGY	2017
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy	SCIENTIFIC REPORTS	2017
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation	CELLULAR SIGNALLING	2017
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells	FREE RADICAL BIOLOGY & MEDICINE	2017
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2017
High glucose and hyperglycemic sera from type 2 diabetic patients impair DC differentiation by inducing ROS and activating Wnt/β-catenin and p38 MAPK	BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE	2016

ERC

LS1_2
LS1_9
LS4_12
LS6
LS6_8

Interessi di ricerca

Risposta immunitaria all'infezione da virus erpetici. Cancerogenesi virale e nuove terapie anti-cancro.

Keywords

Herpesvirus 4

innate immune cells

aggressive cancer

cell death