Daniela Secci

Pubblicazioni

Titolo Pubblicato in Anno
Antimalarial Agents from Medicinal Plant and Fungal Sources Plant-derived Bioactives. Production, Properties and Therapeutic Applications 2020
Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2020
Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2020
Synthesis and biological evaluation of carvacrol-based derivatives as dual inhibitors of H. Pylori strains and ags cell proliferation PHARMACEUTICALS 2020
Innovative pH-interfering agents in association with anticancer agents pH-Interfering Agents as Chemosensitizers in Cancer Therapy 2020
Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles MOLECULES 2019
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2019
Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2019
Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2019
Novel approaches to the discovery of selective human monoamine oxidase-B inhibitors: is there room for improvement? EXPERT OPINION ON DRUG DISCOVERY 2019
Investigation on the stability of new biologically active thiosemicarbazone-derived compounds by a validated HPLC-PDA method CURRENT ANALYTICAL CHEMISTRY 2019
Bioactive isoflavones from Pueraria lobata root and starch: Different extraction techniques and carbonic anhydrase inhibition FOOD AND CHEMICAL TOXICOLOGY 2018
A chromatographic study on the exceptional chiral recognition of 2-(benzylsulfinyl)benzamide by animmobilized-type chiral stationary phase based on cellulose tris(3,5-dichlorophenylcarbamate) JOURNAL OF CHROMATOGRAPHY A 2018
Design, synthesis and biochemical evaluation of novel multi-target inhibitors as potential anti-Parkinson agents EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2018
MAO inhibitors and their wider applications: a patent review EXPERT OPINION ON THERAPEUTIC PATENTS 2018
Magnetic metal−organic framework composite by fast and facile mechanochemical process INORGANIC CHEMISTRY 2018
Atriplex mollis desf. Aerial parts: extraction procedures, secondary metabolites and color analysis MOLECULES 2018
Geographical characterization by MAE-HPLC and NIR methodologies and carbonic anhydrase inhibition of Saffron components FOOD CHEMISTRY 2017
3-(Phenyl-4-oxy)-5-phenyl-4,5-dihydro-(1H)-pyrazole: a fascinating molecular framework to study the enantioseparation ability of the amylose (3,5-dimethylphenylcarbamate) chiral stationary phase. Part II. Solvophobic effects in enantiorecognition process JOURNAL OF CHROMATOGRAPHY A 2017
Synthesis and biological evaluation of anti-Toxoplasma gondii activity of a novel scaffold of thiazolidinone derivatives JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 2017

ERC

  • LS1_13
  • PE5_17
  • PE5_18

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

  1. Progettazione, sintesi e valutazione biologica di nuovi inibitori selettivi sulle mono ammino ossidasi, MAO-A e MAO-B,
  2. Progettazione, sintesi e valutazione biologica di nuovi modulatori epigenetici con particolare riferimento agli inibitori dell’acetiltransferasi (HATs) ad attività apoptotica e citodifferenziante
  3. Progettazione, sintesi e valutazione biologica di nuovi inibitori selettivi delle isoforme IX e XII dell’anidrasi carbonica per il trattamento di patologie tumorali
  4. Sviluppo e la caratterizzazione di anticorpi monoclonali biosimilari per uso terapeutico isolati da piante transgeniche
  5. Sviluppo e sintesi di metal-organic frameworks (MOFs) per applicazioni biomediche.

Keywords

drug design and discovery
Anticancer agents
neuroprotective agents
Anti-Infective Agents

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