Alessandra Marchetti | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity	CELL DEATH & DISEASE	2023
Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity	CELL DEATH & DISEASE	2023
The lncRNA HOTAIR: a pleiotropic regulator of epithelial cell plasticity	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2023
SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Exosome-Associated circRNAs as Key Regulators of EMT in Cancer	CELLS	2022
Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells	CELL DEATH & DISEASE	2022
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells	EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY	2019
TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases	FRONTIERS IN PHARMACOLOGY	2019
YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation	CELL DEATH & DISEASE	2019
Genetica: un approccio molecolare (V edizione)		2019
Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma.	TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY	2018
Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes	STEM CELLS INTERNATIONAL	2016
Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis	STEM CELLS INTERNATIONAL	2016
TGFbeta induces binucleation/polyploidization in hepatocytes through a src-Dependent cytokinesis failure	PLOS ONE	2016
Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte	LIVER INTERNATIONAL	2015
New Tools for Molecular Therapy of Hepatocellular Carcinoma	DISEASES	2015

ERC

LS1_9
LS3_4
LS4_12

KET

Life-science technologies & biotechnologies

Interessi di ricerca

Study of molecular mechanisms involved in hepatocyte differentiation and in the epithelial-to-mesenchymal transition; study of signalling pathways involved in cell response to microenvironment cues (soluble factors and ECM stiffness) driving cell differentiation and tumor progression; identification of new tools for gene therapy of hepatocarcinomas

Keywords

epithelial-to-mesenchymal transition (EMT).

tumor suppression

Signal Transduction

tumor microenvironment

Hepatocellular carcinoma (HCC)