Alessandra Marchetti


Titolo Pubblicato in Anno
Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity CELL DEATH & DISEASE 2023
Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity CELL DEATH & DISEASE 2023
The lncRNA HOTAIR: a pleiotropic regulator of epithelial cell plasticity JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 2023
SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Exosome-Associated circRNAs as Key Regulators of EMT in Cancer CELLS 2022
Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells CELL DEATH & DISEASE 2022
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2019
TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases FRONTIERS IN PHARMACOLOGY 2019
YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation CELL DEATH & DISEASE 2019
Genetica: un approccio molecolare (V edizione) 2019
Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY 2018
Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes STEM CELLS INTERNATIONAL 2016
Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis STEM CELLS INTERNATIONAL 2016
TGFbeta induces binucleation/polyploidization in hepatocytes through a src-Dependent cytokinesis failure PLOS ONE 2016
Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte LIVER INTERNATIONAL 2015
New Tools for Molecular Therapy of Hepatocellular Carcinoma DISEASES 2015


  • LS1_9
  • LS3_4
  • LS4_12


  • Life-science technologies & biotechnologies

Interessi di ricerca

Study of molecular mechanisms involved in hepatocyte differentiation and in the epithelial-to-mesenchymal transition; study of signalling pathways involved in cell response to microenvironment cues (soluble factors and ECM stiffness) driving cell differentiation and tumor progression; identification of new tools for gene therapy of hepatocarcinomas


epithelial-to-mesenchymal transition (EMT).
tumor suppression
Signal Transduction
tumor microenvironment
Hepatocellular carcinoma (HCC)

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