Andrea Arena | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication	BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH	2022
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
The dysregulation of autophagy and ER stress induced by HHV-6A infection activates pro-inflammatory pathways and promotes the release of inflammatory cytokines and cathepsin S by CNS cells	VIRUS RESEARCH	2022
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells	BIOMEDICINES	2022
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells	BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS	2022
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation	CARCINOGENESIS	2022
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway	BIOMEDICINES	2022
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress	CELL DEATH DISCOVERY	2022
P53‐r273h sustains ros, pro‐inflammatory cytokine release and mtor activation while reducing autophagy, mitophagy and ucp2 expression, effects prevented by wtp53	BIOMOLECULES	2021
Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment	BIOMEDICINES	2021
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53	EXPERIMENTAL CELL RESEARCH	2021
New insights into curcumin-and resveratrol-mediated anti-cancer effects	PHARMACEUTICALS	2021
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases	CELL DEATH & DISEASE	2020
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease	NEUROBIOLOGY OF DISEASE	2019
Reduced biliverdin reductase-a levels are associated with early alterations of insulin signaling in obesity	BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE	2019
Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome	REDOX BIOLOGY	2019
Disturbance of redox homeostasis in down syndrome: role of iron dysmetabolism	FREE RADICAL BIOLOGY & MEDICINE	2018
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome	TRANSLATIONAL NEURODEGENERATION	2018
Polyubiquitinylation profile in down syndrome brain before and after the development of Alzheimer neuropathology	ANTIOXIDANTS & REDOX SIGNALING	2017