Ricerc@Sapienza

Roberto Rizzi is a distinguished expert in regenerative medicine, recognized for his leadership and innovation in the development of advanced 3D physiological models and human tissue engineering. His research focuses on introducing and integrating cutting-edge technologies that have significantly advanced the high-profile modeling of human physiology. Rizzi’s laboratory has become a hub for pioneering efforts in creating patient-specific 3D organs, including sophisticated organ-on-chip systems, microfluidic devices, organoids, and mini-organ models. These innovations are instrumental in the translational investigation of new therapeutic strategies, particularly in oncology and regenerative medicine. Roberto Rizzi's contributions have highlighted the essential roles of biophysical, biochemical, and environmental factors in the development of advanced in vitro methods, enhancing the precision and effectiveness of these models. His recent work emphasizes the creation of patient-specific dynamic bioenvironments using induced pluripotent stem cells (iPSCs), immunocompetent organoids, and customized biological sensors integrated with Machine Learning (ML) technologies. With his expertise in extrusion-based 3D bioprinting, Roberto Rizzi has successfully replicated the hierarchical structures of natural human organs, pushing the boundaries of personalized medicine. His leadership has not only propelled his team to the forefront of biomedical research but has also positioned them as key contributors to the future of healthcare and therapeutic innovation.