Roberta Santarelli | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
New insights into the Bortezomib‐induced cytotoxic and resistance mechanisms in a primary effusion lymphoma mouse model	HEMATOLOGICAL ONCOLOGY	2024
EZH2 Inhibition by DS3201 triggers the kaposi’s sarcoma-associated herpesvirus lytic cycle and potentiates the effects induced by SAHA in primary effusion lymphoma cells	VIRUSES	2024
EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?	BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS	2024
Different outcome of targeting ERN1/IRE1 alpha and EIF2AK3/PERK in NSG mice engrafted with primary effusion lymphoma	BRITISH JOURNAL OF HAEMATOLOGY	2023
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice	MICROBIOLOGY SPECTRUM	2023
HSP110 Inhibition in Primary Effusion Lymphoma Cells: One Molecule, Many Pro-Survival Targets	CANCERS	2023
NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
HSPs/STAT3 Interplay Sustains DDR and Promotes Cytokine Release by Primary Effusion Lymphoma Cells	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
NRF2 and STAT3: friends or foes in carcinogenesis?	DISCOVER ONCOLOGY	2023
Acetylation increases expression, interaction with TRAPPC4 and surface localization of PD-L1	DISCOVER ONCOLOGY	2023
EBV infection of primary colonic epithelial cells causes inflammation, DDR and autophagy dysregulation, effects that may predispose to IBD and carcinogenesis	VIRUS RESEARCH	2023
Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation	BIOLOGY	2022
3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]pyrene in Primary Human Colonic Epithelial Cells	PHARMACEUTICS	2022
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation	CARCINOGENESIS	2022
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Mechanisms of Sensitivity and Resistance of Primary Effusion Lymphoma to Dimethyl Fumarate (DMF)	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Ire1 alpha/xbp1 axis sustains primary effusion lymphoma cell survival by promoting cytokine release and stat3 activation	BIOMEDICINES	2021
Antiviral filtering capacity of go-coated textiles	APPLIED SCIENCES	2021
Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment	BIOMEDICINES	2021
Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross-talk with p53 to activate p21	IUBMB LIFE	2021

ERC

LS3_2
LS4_12
LS6_6

KET

Life-science technologies & biotechnologies

Interessi di ricerca

EBV and KSHV gammaherpesviruses: biology, immune escape strategies and molecular mechanisms of oncogenesis.
Novel treatments of EBV- and KSHV-associated malignancies.

Keywords

Herpesvirus 8

Herpesvirus 4

Autophagy/UPR

endmt

EMT Epithelial-Mesenchymal Transition

immune escape

primary effusion lymphoma