Francesca Belleudi | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
TRPA1 Contributes to FGFR2c Signaling and to Its Oncogenic Outcomes in Pancreatic Ductal Adenocarcinoma-Derived Cell Lines	CANCERS	2024
FGFR2c Upregulation Contributes to Cancer-Associated Fibroblast Program Activation and to Enhanced Autophagy in Actinic Keratosis-Derived Dermal Fibroblasts: A Possible Role in Precancerous Cell/Stromal Cell Crosstalk	BIOLOGY	2023
The FGFR2c/PKCε Axis Controls MCL-1-Mediated Invasion in Pancreatic Ductal Adenocarcinoma Cells: Perspectives for Innovative Target Therapies	BIOMEDICINES	2022
The aberrant expression in epithelial cells of the mesenchymal isoform of FGFR2 controls the negative crosstalk between EMT and autophagy	JOURNAL OF CELLULAR AND MOLECULAR MEDICINE	2021
Expression profile of fibroblast growth factor receptors, keratinocyte differentiation markers, and epithelial mesenchymal transition-related genes in actinic keratosis. A possible predictive factor for malignant progression?	BIOLOGY	2021
Expression of the e5 oncoprotein of hpv16 impacts on the molecular profiles of emt-related and differentiation genes in ectocervical low-grade lesions	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2021
Role of fgfr2c and its pkcε downstream signaling in the control of emt and autophagy in pancreatic ductal adenocarcinoma cells	CANCERS	2021
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)	AUTOPHAGY	2021
Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switch	CELL COMMUNICATION AND SIGNALING	2020
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)	AUTOPHAGY	2020
The aberrant expression of the mesenchymal variant of FGFR2 in the epithelial context inhibits autophagy	CELLS	2019
Interplay between FGFR2b-induced autophagy and phagocytosis: role of PLCÎ³-mediated signalling	JOURNAL OF CELLULAR AND MOLECULAR MEDICINE	2018
Expression of the FGFR2c mesenchymal splicing variant in human keratinocytes inhibits differentiation and promotes invasion	MOLECULAR CARCINOGENESIS	2018
Role of FGFR2b in the crosstalk between autophagy and differentiation: involvement of JNK signaling	MOLECULAR AND CELLULAR BIOLOGY	2018
Role of FGFR2b expression and signaling in keratinocyte differentiation. Sequential involvement of PKCδ and PKCα	CELL DEATH & DISEASE	2018
Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells	FRONTIERS IN IMMUNOLOGY	2018
Tumor-derived microvesicles modulate antigen cross-processing via reactive oxygen species-mediated alkalinization of phagosomal compartment in dendritic cells	FRONTIERS IN IMMUNOLOGY	2017
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)	AUTOPHAGY	2016
Expression of the FGFR2 mesenchymal splicing variant in epithelial cells drives epithelial-mesenchymal transition	ONCOTARGET	2016
HPV16 E5 expression induces switching from FGFR2b to FGFR2c and epithelial-mesenchymal transition	INTERNATIONAL JOURNAL OF CANCER	2015

Progetti di Ricerca

FGFR isoform switch in pancreatic ductal adenocarcinoma: role of FGFR2c aberrant expression and signaling in the establishment of EMT and dysregulated autophagy.
Role of FGFR isoform switch during carcinogenesis: interplay between receptor oncogenic signaling, endocytosis and EMT.
Role of FGFR2b and its PKC-mediated signaling in the regulation of epithelial cell diffentiation.
Crosstalk between autophagy and epithelial-mesenchymal transition: role of FGFR2 altered splicing
Molecular mechanisms underlying the negative interplay between autophagy and epithelial-mesenchymal transition: possible role of FGFR2c signaling pathways.

Laboratori di ricerca

laboratorio di coltura cellulare