Alessandra Pierangeli

Pubblicazioni

Titolo Pubblicato in Anno
High prevalence of Merkel cell polyomavirus is associated with dysregulation in transcript levels of TLR9 and type I IFNs in a large cohort of CF patients from the Italian (Lazio) reference center for cystic fibrosis MICROBIAL PATHOGENESIS 2022
The non-functional ACE2 isoform, but not the SARS-CoV-2 receptor, is induced as an interferon-stimulated gene, in SARS-CoV-2 infected adults CYTOKINE 2022
Low lymphocyte count: A clinical severity marker in infants with bronchiolitis PEDIATRIC PULMONOLOGY 2022
An Italian Multicenter Study on the Epidemiology of Respiratory Syncytial Virus During SARS-CoV-2 Pandemic in Hospitalized Children FRONTIERS IN PEDIATRICS 2022
Efficacy of antiseptic mouthrinses against SARS-CoV-2: A prospective randomized placebo-controlled pilot study AMERICAN JOURNAL OF OTOLARYNGOLOGY 2022
Common microbial genital infections and their impact on the innate immune response to HPV in cervical cells PATHOGENS 2022
High frequency of neutralizing antibodies to type I Interferon in HIV-1 patients hospitalized for COVID-19 CLINICAL IMMUNOLOGY 2022
Multicenter epidemiological investigation and genetic characterization of respiratory syncytial virus and metapneumovirus infections in the pre-pandemic 2018-2019 season in northern and central Italy CLINICAL AND EXPERIMENTAL MEDICINE 2022
Efficacy of antiseptic mouthrinses against SARS-CoV-2: A prospective randomized placebo-controlled pilot study AMERICAN JOURNAL OF OTOLARYNGOLOGY 2022
SARS-CoV-2 Entry Genes Expression in Relation with Interferon Response in Cystic Fibrosis Patients MICROORGANISMS 2021
Differential induction of type I and III interferon genes in the upper respiratory tract of patients with coronavirus disease 2019 (COVID-19) VIRUS RESEARCH 2021
ACE2 expression is related to the interferon response in airway epithelial cells but is that functional for SARS-CoV-2 entry? CYTOKINE 2021
Viral community acquired pneumonia at the emergency department: report from the pre COVID-19 age JOURNAL OF MEDICAL VIROLOGY 2021
KI and WU polyomavirus in respiratory samples of sars‐cov‐2 infected patients MICROORGANISMS 2021
The starting rate for high-flow nasal cannula oxygen therapy in infants with bronchiolitis: is clinical judgment enough? PEDIATRIC PULMONOLOGY 2021
During the COVID-19 pandemic where has respiratory syncytial virus gone? PEDIATRIC PULMONOLOGY 2021
Clinical effects of oral bacteriotherapy on anal hpv infection and related dysplasia in hiv-positive msm: Results from the “hpvinhiv” trial BIOMEDICINES 2021
Increased T-helper cell 2 response in infants with respiratory syncytial virus bronchiolitis hospitalized outside epidemic peak THE PEDIATRIC INFECTIOUS DISEASE JOURNAL 2020
Novel variants of respiratory syncytial virus A ON1 associated with increased clinical severity of bronchiolitis THE JOURNAL OF INFECTIOUS DISEASES 2020
A single centre study of viral community-acquired pneumonia in children: no evidence of SARSCoV-2 from october 2019 to march 2020 JOURNAL OF CLINICAL VIROLOGY 2020

ERC

  • LS6_3
  • LS6_6

Interessi di ricerca

Caratterizzazione molecolare ed epidemiologica dei virus respiratori; il contributo della risposta immune dell’ospite alla patogenesi e alle sequele respiratorie. Di particolare rilevanza: caratterizzazione clinica e virologica di virus respiratori emergenti (Metapneumovirus, Bocavirus), del virus influenza A (H1N1) responsabile della pandemia del 2009 in malati di età  pediatrica e adulta e del Virus Respiratorio Sinciziale (RSV), con la prima rilevazione in Europa del nuovo ceppo ON1 sottotipo A, e degli altri genotipi di RSV-A e -B circolanti in Italia, in collaborazione con altri gruppi di ricerca a livello nazionale. Studio della risposta immunitaria innata e acquisita in pazienti COVID-19 e in bambini positivi a SARS-CoV-2.

Diagnosi molecolare di Papillomavirus (HPV) DNA in collaborazione coi clinici (ginecologi, dermatologi, proctologi, otorinolaringoiatri, infettivologi), rafforzamento della consapevolezza del poteziale oncogenico di HPV; epidemiologia, caratterizzazione molecolare e analisi della carica virale in infezioni da HPV con localizzazione genitale, anale, orofaringea e cutanea; attivazione di geni interferon-indotti in pazienti infetti; ruolo del microbiota nella storia naturale di HPV

 

Infezioni umane e sorveglianza ambientale di Enterovirus

 

Keywords

virus respiratorio sinciziale
pneumonia: Sars-Cov-2
HPV
immunità innata
Enterovirus 

Progetti di Ricerca

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