Alessandra Pierangeli

Pubblicazioni

Titolo Pubblicato in Anno
The epidemiology of Anal Human Papillomavirus (HPV) in HIV-Positive and HIV-Negative women and men: a ten-year retrospective observational study in Rome (Italy) PATHOGENS 2024
The Epidemiology of Anal Human Papillomavirus (HPV) in HIV-Positive and HIV-Negative Women and Men: A Ten-Year Retrospective Observational Study in Rome (Italy) PATHOGENS 2024
Age-related transcript changes in type I interferon signaling in children and adolescents with long COVID EUROPEAN JOURNAL OF IMMUNOLOGY 2024
SARS-CoV-2–specific mucosal immune response in vaccinated versus infected children FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY 2024
Sequence analysis of respiratory syncytial virus cases reveals a novel subgroup -B strain circulating in north-central Italy after pandemic restrictions JOURNAL OF CLINICAL VIROLOGY 2024
Natural Flavonoid Derivatives Have Pan-Coronavirus Antiviral Activity MICROORGANISMS 2023
Alterations in the Expression of IFN Lambda, IFN Gamma and Toll-like Receptors in Severe COVID-19 Patients MICROORGANISMS 2023
NRF2 Antioxidant Response and Interferon-Stimulated Genes Are Differentially Expressed in Respiratory-Syncytial-Virus- and Rhinovirus-Infected Hospitalized Children PATHOGENS 2023
Alterations in the Expression of IFN Lambda, IFN Gamma and Toll-like Receptors in Severe COVID-19 Patients MICROORGANISMS 2023
In Vitro Virucidal Effects of Ultraviolet Light Prototypes on RNA viruses NEW MICROBIOLOGICA 2023
Genetic diversity and its impact on disease severity in respiratory syncytial virus subtype-A and -B bronchiolitis before and after pandemic restrictions in Rome JOURNAL OF INFECTION 2023
An overview on viral interference during SARS-CoV-2 pandemic FRONTIERS IN PEDIATRICS 2023
Molecular study of the presence and transcriptional activity of HPV in semen JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 2023
Detection of Human Papillomavirus infection in oral mucosal diseases: a single-center study. JADA Foundational Science 2023
HPV vaccination after primary treatment of HPV-related disease across different organ sites: a multidisciplinary comprehensive review and meta-analysis VACCINES 2022
Modifiable environmental factors predispose term infants to bronchiolitis but bronchiolitis itself predisposes to respiratory sequelae PEDIATRIC PULMONOLOGY 2022
Bronchiolitis phenotypes identified by latent class analysis may influence the occurrence of respiratory sequelae PEDIATRIC PULMONOLOGY 2022
Distribution of Interferon Lambda 4 Single Nucleotide Polymorphism rs11322783 Genotypes in Patients with COVID-19 MICROORGANISMS 2022
The first COVID-19 lockdown resulted in most respiratory viruses disappearing among hospitalised children, with the exception of rhinoviruses ACTA PAEDIATRICA 2022
Anti-IFN-α/-ω neutralizing antibodies from COVID-19 patients correlate with downregulation of IFN response and laboratory biomarkers of disease severity EUROPEAN JOURNAL OF IMMUNOLOGY 2022

ERC

  • LS6_3
  • LS6_6

Interessi di ricerca

Caratterizzazione molecolare ed epidemiologica dei virus respiratori; il contributo della risposta immune dell’ospite alla patogenesi e alle sequele respiratorie. Di particolare rilevanza: caratterizzazione clinica e virologica di virus respiratori emergenti (Metapneumovirus, Bocavirus), del virus influenza A (H1N1) responsabile della pandemia del 2009 in malati di età  pediatrica e adulta e del Virus Respiratorio Sinciziale (RSV), con la prima rilevazione in Europa del nuovo ceppo ON1 sottotipo A, e degli altri genotipi di RSV-A e -B circolanti in Italia, in collaborazione con altri gruppi di ricerca a livello nazionale. Studio della risposta immunitaria innata e acquisita in pazienti COVID-19 e in bambini positivi a SARS-CoV-2.

Diagnosi molecolare di Papillomavirus (HPV) DNA in collaborazione coi clinici (ginecologi, dermatologi, proctologi, otorinolaringoiatri, infettivologi), rafforzamento della consapevolezza del poteziale oncogenico di HPV; epidemiologia, caratterizzazione molecolare e analisi della carica virale in infezioni da HPV con localizzazione genitale, anale, orofaringea e cutanea; attivazione di geni interferon-indotti in pazienti infetti; ruolo del microbiota nella storia naturale di HPV

 

Infezioni umane e sorveglianza ambientale di Enterovirus

 

Keywords

virus respiratorio sinciziale
pneumonia: Sars-Cov-2
HPV
immunità innata
Enterovirus 

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