Valentina Noemi Madia

Pubblicazioni

Titolo Pubblicato in Anno
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site MOLECULES 2023
Pyrrolyl and indolyl α-γ-diketo acid derivatives acting as selective inhibitors of human carbonic anhydrases IX and XII PHARMACEUTICALS 2023
Plants and Small Molecules: An Up-and-Coming Synergy PLANTS 2023
Synergistic Effects of Caffeine in Combination with Conventional Drugs: Perspectives of a Drug That Never Ages PHARMACEUTICALS 2023
Effects of Modified Glucosamine on the Chondrogenic Potential of Circulating Stem Cells under Experimental Inflammation INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023
Diketo acid inhibitors of nsp13 of SARS-CoV-2 block viral replication ANTIVIRAL RESEARCH 2023
Role of a Novel Heparanase Inhibitor on the Balance between Apoptosis and Autophagy in U87 Human Glioblastoma Cells CELLS 2023
Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors JOURNAL OF MEDICINAL CHEMISTRY 2023
Oxidative stress and visual system a review EXCLI JOURNAL 2022
Design, synthesis, and In vitro, in silico and in cellulo evaluation of new Pyrimidine and Pyridine amide and Carbamate derivatives as multi-functional Cholinesterase Inhibitors PHARMACEUTICALS 2022
Ultrastructural damages to H1N1 influenza virus caused by vapor essential oils MOLECULES 2022
New Inhibitors of the Human p300/CBP Acetyltransferase Are Selectively Active against the Arabidopsis HAC Proteins INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022
Acetylcholinesterase inhibitors for the treatment of Alzheimer’s disease–a patent review (2016–present) EXPERT OPINION ON THERAPEUTIC PATENTS 2021
Design, synthesis and biological evaluation of new pyrimidine derivatives as anticancer agents MOLECULES 2021
Investigation of Commiphora myrrha (Nees) Engl. Oil and Its Main Components for Antiviral Activity PHARMACEUTICALS 2021
Analytical characterization of an inulin-type fructooligosaccharide from root-tubers of Asphodelus ramosus L PHARMACEUTICALS 2021
Anti-tumoral effects of a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative on head and neck squamous carcinoma cell lines PHARMACEUTICALS 2021
Quinolinonyl non-diketo acid derivatives as Inhibitors of HIV-1 ribonuclease H and polymerase functions of reverse transcriptase JOURNAL OF MEDICINAL CHEMISTRY 2021
Recent advances in recovery of lycopene from tomato waste. A potent antioxidant with endless benefits MOLECULES 2021
Toxicological aspects of cannabinoid, pesticide and metal levels detected in light Cannabis inflorescences grown in Italy FOOD AND CHEMICAL TOXICOLOGY 2021

ERC

  • PE5_18

KET

  • Life-science technologies & biotechnologies

Interessi di ricerca

Drug Design.

Antimicrobial agents active agains virues such as HIV, SARSCoV, HCV, CHIKV,

Antibacterial agents based on quinolone scaffold. Metallo-beta-lactamase inhibitors.

Antiprotozoals

Antifungals

Antimycobacterals

Antitumor agenst with specific mechanism of action: Kinase Inhibitors. Inhibitors of tubulin polimerization. Antitumoral agents found by phenotypic approach.

Natural substances: plant extracts for medicinal and nutraceutical applications.

Keywords

drug design and synthesis.
antiviral agents
antibacterial agents
antifungal agents
Antiprotozoal Agents
antimycobacterial agents
antitumor agents

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