Giuseppe Esposito | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages	METABOLITES	2021
Pentamidine niosomes thwart S100B effects in human colon carcinoma biopsies favouring wtp53 rescue	JOURNAL OF CELLULAR AND MOLECULAR MEDICINE	2020
Can the enteric nervous system be an alternative entrance door in SARS-CoV2 neuroinvasion?	BRAIN BEHAVIOR AND IMMUNITY	2020
The potential of cannabidiol in the COVID-19 pandemic: a hypothesis letter	BRITISH JOURNAL OF PHARMACOLOGY	2020
Lathyrus sativus diamine oxidase reduces clostridium difficile toxin a-induced toxicity in caco-2 cells by rescuing rhoa-gtpase and inhibiting pp38-mapKknf-κb/hif-1α activation	PHYTOTHERAPY RESEARCH	2020
Impaired Duodenal Palmitoylethanolamide Release Underlies Acid-Induced Mast Cell Activation in Functional Dyspepsia	CMGH	2020
Phytotherapics in COVID19: Why palmitoylethanolamide?	PHYTOTHERAPY RESEARCH	2020
inPentasomes: an innovative nose-to-brain pentamidine delivery blunts MPTP parkinsonism in mice	JOURNAL OF CONTROLLED RELEASE	2019
Lathyrus sativus diamine oxidase counteracts histamine-induced cell proliferation, migration and pro-angiogenic mediators release in human colon adenocarcinoma cell line caco-2	PHYTOTHERAPY RESEARCH	2019
Play in advance against neurodegeneration: exploring enteric glial cells in gut-brain axis during neurodegenerative diseases	EXPERT REVIEW OF CLINICAL PHARMACOLOGY	2019
Leaky gut, dysbiosis, and enteric glia activation: the trilogy behind the intestinal origin of Parkinson's disease	NEURAL REGENERATION RESEARCH	2019
S100B protein stimulates proliferation and angiogenic mediators release through RAGE/pAkt/mTOR pathway in human colon adenocarcinoma Caco-2 Cells	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2019
Endocannabinoid-related compounds in gastrointestinal diseases	JOURNAL OF CELLULAR AND MOLECULAR MEDICINE	2018
HIV-1 Tat-induced diarrhea is improved by the PPAR alpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia	JOURNAL OF NEUROINFLAMMATION	2018
Endocannabinoids in the treatment of gasytrointestinal inflammation and symptoms	CURRENT OPINION IN PHARMACOLOGY	2018
HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system	SCIENTIFIC REPORTS	2017
Cannabidiol restores intestinal barrier dysfunction and inhibits the apoptotic process induced by Clostridium difficile toxin A in Caco-2 cells	UNITED EUROPEAN GASTROENTEROLOGY JOURNAL	2017
Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in β amyloid-induced neurodegeneration	SCIENTIFIC REPORTS	2016
Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-α-Dependent Inhibition of Akt/mTOR Pathway	PHYTOTHERAPY RESEARCH	2016
Rifaximin improves clostridium difficile toxin A-induced toxicity in caco-2 cells by the PXR-dependent TLR4/MyD88/NF-κB pathway	FRONTIERS IN PHARMACOLOGY	2016

Progetti di Ricerca

Enteric glia activation and gut microbioma changes: the perfect storm promoting tardive onset of neurocognitive dysfunctions induced by intestinal sepsis through a gut-brain axis route in mice.
Leaky gut induction by antibiotic overexposure: hypothesis for a gut-brain axis connection triggering parkinsonism-related neuropathology through enteric glia activation in mice.