Giuseppe Esposito | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Intranasal delivery of PEA-producing Lactobacillus paracasei F19 alleviates SARSCoV- 2 spike protein-induced lung injury in mice	TRANSLATIONAL MEDICINE COMMUNICATIONS	2024
Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein-mediated lung injury in mice	BIOMEDICINE & PHARMACOTHERAPY	2024
Gut-directed therapy in Parkinson’s disease	FRONTIERS IN PHARMACOLOGY	2024
Clinical and nutritional correlates associated with weight changes in achalasia patients and the impact of laparoscopic Heller myotomy	DIGESTIVE AND LIVER DISEASE	2024
N-palmitoyl-D-glucosamine limits mucosal damage and VEGFmediated angiogenesis by PPARα-dependent suppression of pAkt/mTOR/HIF1α pathway and increase in PEA levels in AOM/DSS colorectal carcinoma in mice	PHYTOTHERAPY RESEARCH	2024
S100B Affects Gut Microbiota Biodiversity	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice	BIOMOLECULES	2023
Mini-review: Interaction between intestinal microbes and enteric glia in health and disease	NEUROSCIENCE LETTERS	2023
Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors	JOURNAL OF MEDICINAL CHEMISTRY	2023
Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
Nutraceuticals and Diet Supplements in Crohn’s Disease: A General Overview of the Most Promising Approaches in the Clinic	FOODS	2022
Oral Adelmidrol Administration Up-Regulates Palmitoylethanolamide Production in Mice Colon and Duodenum through a PPAR-γ Independent Action	METABOLITES	2022
Next-Generation Probiotics for Inflammatory Bowel Disease	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
Sleeve Gastrectomy-Induced Body Mass Index Reduction Increases the Intensity of Taste Perception’s and Reduces Bitter-Induced Pleasantness in Severe Obesity	JOURNAL OF CLINICAL MEDICINE	2022
N-Palmitoyl-D-Glucosamine Inhibits TLR-4/NLRP3 and Improves DNBS-Induced Colon Inflammation through a PPAR-α-Dependent Mechanism	BIOMOLECULES	2022
Enteric inflammation and chronic diseases: Is there a link ?	FRONTIERS IN PHARMACOLOGY	2022
Editorial: Implications of gut-brain interactions for the effects of compounds derived from Cannabis or modulating the endocannabinoid system in physiological and pathological processes	FRONTIERS IN CELLULAR NEUROSCIENCE	2022
Functional Intraregional and Interregional Heterogeneity between Myenteric Glial Cells of the Colon and Duodenum in Mice	THE JOURNAL OF NEUROSCIENCE	2022
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2021
A Palmitoylethanolamide Producing Lactobacillus paracasei Improves Clostridium difficile Toxin A-Induced Colitis	FRONTIERS IN PHARMACOLOGY	2021

Progetti di Ricerca

Enteric glia activation and gut microbioma changes: the perfect storm promoting tardive onset of neurocognitive dysfunctions induced by intestinal sepsis through a gut-brain axis route in mice.
Leaky gut induction by antibiotic overexposure: hypothesis for a gut-brain axis connection triggering parkinsonism-related neuropathology through enteric glia activation in mice.

Laboratori di ricerca

Laboratorio di farmacologia del sistema nervoso enterico (Dipartimento Fisiologia & Farmacologia – CU024)