Esterina Pascale


Titolo Pubblicato in Anno
How can CpG methylations, and pair-to-pair correlations between the main (gene) and the opposite strands, suggest a bending DNA loop. Insights into the 5′-UTR of DAT1 GENES 2023
Methylation Dynamics on 5′-UTR of DAT1 Gene as a Bio-Marker to Recognize Therapy Success in ADHD Children CHILDREN 2023
DAT1 5′-Un-Translated-Region methylation patterns as bio-markers of ADHD psycho-pathology. Contribution to disease prognosis and to monitoring of a successful therapy BIOMEDICINES 2023
Cladribine and ocrelizumab induce differential miRNA profiles in peripheral blood mononucleated cells from relapsing-remitting multiple sclerosis patients FRONTIERS IN IMMUNOLOGY 2023
Disordered eating in early childhood: DRD4 and DAT1 gene polymorphisms and quality of mother–child interaction EATING AND WEIGHT DISORDERS 2022
Methylation patterns within 5'-UTR of DAT1 gene as a function of allelic 3'-UTR variants and their maternal or paternal origin: may these affect the psychopathological phenotypes in children? An explorative study NEUROSCIENCE LETTERS 2022
Genetics influences drug consumption in medication overuse headache, not in migraine. Evidence from Wolframin His611Arg polymorphism analysis FRONTIERS IN NEUROLOGY 2021
Epigenetic regulation of DAT gene promoter modulates the risk of Externalizing and Internalizing behaviors on a normative population: an explorative study BEHAVIOURAL BRAIN RESEARCH 2021
Interazione gene- ambiente e rischio psicopatologico in età scolare. Il ruolo del genotipo DAT1 del bambino e dell’ambiente affettivo familiare PSICOLOGIA CLINICA DELLO SVILUPPO 2021
DNA methylation of the 5'-UTR DAT 1 gene in Parkinson's disease patients ACTA NEUROLOGICA SCANDINAVICA 2020
DAT1 Gene methylation as an epigenetic biomarker in attention deficit hyperactivity disorder. A commentary FRONTIERS IN GENETICS 2020
Cross-correlations between motifs in the 5′-UTR of DAT1 gene. Findings from Parkinson’s disease ADVANCES IN BIOLOGICAL REGULATION 2020
Associations Among Internet Addiction, Genetic Polymorphisms, Family Functioning, and Psychopathological Risk: Cross-Sectional Exploratory Study JMIR. JOURNAL OF MEDICAL INTERNET RESEARCH 2020
Search for an epigenetic biomarker in ADHD diagnosis, based on the DAT1 gene 5’-UTR methylation: a new possible approach PSYCHIATRY RESEARCH 2020
Involvement of DAT1 gene on internet addiction: Cross-correlations of methylation levels in 5'-utr and 3’-UTR genotypes, interact with impulsivity and attachment-driven quality of relationships INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2020
Beyond the dyad: the role of mother and father in newborns’ global DNA methylation during the first month of life—a pilot study DEVELOPMENTAL PSYCHOBIOLOGY 2020
DAT gene polymorphisms (rs28363170, rs393795) and levodopa-induced dyskinesias in Parkinson's disease NEUROSCIENCE LETTERS 2019
On the role of adenosine a2a receptor gene transcriptional regulation in parkinson’s disease FRONTIERS IN NEUROSCIENCE 2019
Children’s DAT1 polymorphism moderates the relationship between parents’ psychological profiles, children’s DAT methylation, and their emotional/behavioral functioning in a normative sample INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2019
Potential for diagnosis versus therapy monitoring of attention deficit hyperactivity disorder: a new epigenetic biomarker interacting with both genotype and auto-immunity EUROPEAN CHILD & ADOLESCENT PSYCHIATRY 2018


  • LS1_3
  • LS2_1
  • LS2_3
  • LS5_8
  • LS5_11


  • Life-science technologies & biotechnologies

Interessi di ricerca

Studio di polimorfismi genici in alcune malattie neurodegenerative umane, in particolare nella malattia di Parkinson, come punto di partenza per comprendere i meccanismi molecolari alla base della malattia e per l’identificazione di nuovi target per lo sviluppo di terapie innovative.

Ruolo dei polimorfismi genici di selezionati neurotrasmettitori nella suscettibilità alle dipendenze da alcol, internet gaming e disordini alimentari.

Analisi del profilo di metilazione di selezionati neurotrasmettitori


dopamine transporter (DAT
Alcohol addiction
Attention Deficit Disorder with Hyperactivity
gene polymorphis
genetics and molecular biolog
parkinson's diseas
Serotonin Transporte
single nucleotide polymorphis

Gruppi di ricerca

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