Rocco Palermo


Titolo Pubblicato in Anno
Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey-Hailey disease EXPERIMENTAL DERMATOLOGY 2023
5FU/Oxaliplatin-induced Jagged1 cleavage counteracts apoptosis induction in colorectal cancer: a novel mechanism of intrinsic drug resistance FRONTIERS IN ONCOLOGY 2022
Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALL CANCERS 2022
When viruses cross developmental pathways FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2021
Targeting notch to maximize chemotherapeutic benefits: rationale, advanced strategies, and future perspectives CANCERS 2021
Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response ONCOGENESIS 2020
Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL FRONTIERS IN ONCOLOGY 2019
Chalcones and chalcone-mimetic derivatives as Notch inhibitors in a model of T-cell Acute Lymphoblastic Leukemia ACS MEDICINAL CHEMISTRY LETTERS 2019
Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains CRC progression and chemoresistance CANCER RESEARCH 2019
PLK1 targets NOTCH1 during DNA damage and mitotic progression THE JOURNAL OF BIOLOGICAL CHEMISTRY 2019
Notch3 contributes to T-cell leukemia growth via regulation of the unfolding protein response The Biennial Congress of the Italian Association of cell biology and differentiation 2019
Notch signaling as a therapeutic target for acute lymphoblastic leukemia EXPERT OPINION ON THERAPEUTIC TARGETS 2018
NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest. ONCOGENESIS 2018
Targeting the ER/UPR signalling in Notch3-overexpressing T-cell acute lymphoblastic leukemia. Atti del ABCD - Ph.D. meeting 2018
The Notch3 receptor and its intracellular signaling-dependent oncogenic mechanisms Molecular Mechanisms of Notch Signaling 2018
Natural products inspired modulators of cancer stem cells-specific signaling pathways notch and hedgehog CURRENT PHARMACEUTICAL DESIGN 2018
Potential targeted therapy for T-cell acute lymphoblastic leukemia: perturbing ER/UPR signaling via Notch3 down-regulation Cell communication and signaling: how to turn bad language into positive one 2018
Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells NANOMEDICINE 2017
Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia SCIENTIFIC REPORTS 2017


  • LS4_12


  • Life-science technologies & biotechnologies


Notch pathway
NF-kappa B
anti-tumor agents
epigenetic modulators
Notch inhibitors

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