Rossella Benedetti | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
New insights into the Bortezomib‐induced cytotoxic and resistance mechanisms in a primary effusion lymphoma mouse model	HEMATOLOGICAL ONCOLOGY	2024
5-AZA Upregulates SOCS3 and PTPN6/SHP1, Inhibiting STAT3 and Potentiating the Effects of AG490 against Primary Effusion Lymphoma Cells	CURRENT ISSUES IN MOLECULAR BIOLOGY	2024
ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression	AUTOPHAGY	2024
Recent Advances on Mutant p53: Unveiling Novel Oncogenic Roles, Degradation Pathways, and Therapeutic Interventions	BIOMOLECULES	2024
SAHA/5-AZA Enhances Acetylation and Degradation of mutp53, Upregulates p21 and Downregulates c-Myc and BRCA-1 in Pancreatic Cancer Cells	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2024
Post-translational modifications (PTMs) of mutp53 and epigenetic changes induced by mutp53	BIOLOGY	2024
EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?	BIOCHIMICA ET BIOPHYSICA ACTA. GENE REGULATORY MECHANISMS	2024
Different outcome of targeting ERN1/IRE1 alpha and EIF2AK3/PERK in NSG mice engrafted with primary effusion lymphoma	BRITISH JOURNAL OF HAEMATOLOGY	2023
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice	MICROBIOLOGY SPECTRUM	2023
HSP110 Inhibition in Primary Effusion Lymphoma Cells: One Molecule, Many Pro-Survival Targets	CANCERS	2023
NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2023
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms	EXPERIMENTAL HEMATOLOGY	2023
NRF2 and STAT3: friends or foes in carcinogenesis?	DISCOVER ONCOLOGY	2023
Acetylation increases expression, interaction with TRAPPC4 and surface localization of PD-L1	DISCOVER ONCOLOGY	2023
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication	BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH	2022
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES	2022
The dysregulation of autophagy and ER stress induced by HHV-6A infection activates pro-inflammatory pathways and promotes the release of inflammatory cytokines and cathepsin S by CNS cells	VIRUS RESEARCH	2022
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells	BIOMEDICINES	2022
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells	BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS	2022
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation	CARCINOGENESIS	2022

ERC

LS3_2
LS4_12

KET

Life-science technologies & biotechnologies

Keywords

endoplasmic reticulum (ER stress)

mutant p53 (mutp53)