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rossella.benedetti@uniroma1.it
Rossella Benedetti
Dottorando
Struttura:
DIPARTIMENTO DI MEDICINA CLINICA E MOLECOLARE
E-mail:
rossella.benedetti@uniroma1.it
Pagina istituzionale corsi di laurea
Curriculum Sapienza
Pubblicazioni
Titolo
Pubblicato in
Anno
Different outcome of targeting ERN1/IRE1 alpha and EIF2AK3/PERK in NSG mice engrafted with primary effusion lymphoma
BRITISH JOURNAL OF HAEMATOLOGY
2023
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice
MICROBIOLOGY SPECTRUM
2023
DNA damage triggers an interplay between wtp53 and c-Myc affecting lymphoma cell proliferation and Kaposi sarcoma herpesvirus replication
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
2022
VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
The dysregulation of autophagy and ER stress induced by HHV-6A infection activates pro-inflammatory pathways and promotes the release of inflammatory cytokines and cathepsin S by CNS cells
VIRUS RESEARCH
2022
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells
BIOMEDICINES
2022
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
2022
p62/SQSTM1 promotes mitophagy and activates the NRF2-mediated antioxidant and anti-inflammatory response restraining EBV-driven B lymphocyte proliferation
CARCINOGENESIS
2022
c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway
BIOMEDICINES
2022
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress
CELL DEATH DISCOVERY
2022
P53‐r273h sustains ros, pro‐inflammatory cytokine release and mtor activation while reducing autophagy, mitophagy and ucp2 expression, effects prevented by wtp53
BIOMOLECULES
2021
The cross-talk between STAT1/STAT3 and ROS up-regulates PD-L1 and promotes the release of pro-inflammatory/immune suppressive cytokines in primary monocytes infected by HHV-6B
VIRUS RESEARCH
2021
PGE2 released by pancreatic cancer cells undergoing ER stress transfers the stress to DCs impairing their immune function
MOLECULAR CANCER THERAPEUTICS
2021
Role of upr sensor activation in cell death–survival decision of colon cancer cells stressed by dpe treatment
BIOMEDICINES
2021
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53
EXPERIMENTAL CELL RESEARCH
2021
New insights into curcumin-and resveratrol-mediated anti-cancer effects
PHARMACEUTICALS
2021
PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR
BIOMOLECULES
2020
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway
FRONTIERS IN ONCOLOGY
2020
Viral Infection and Autophagy Dysregulation: The Case of HHV-6, EBV and KSHV
CELLS
2020
ERC
LS3_2
LS4_12
KET
Life-science technologies & biotechnologies
Keywords
endoplasmic reticulum (ER stress)
mutant p53 (mutp53)
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