Giuseppe Giannini | Ricerc@Sapienza

Pubblicazioni

Titolo	Pubblicato in	Anno
Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations	HUMAN MUTATION	2018
Effective treatment of a platinum-resistant cutaneous squamous cell carcinoma case by EGFR pathway inhibition	MOLECULAR AND CLINICAL ONCOLOGY	2018
Coexistence of three EGFR mutations in an NSCLC patient: A brief report	THE INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS	2018
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors	CELL DEATH & DISEASE	2018
Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma	CANCER CELL	2017
Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production	ONCOIMMUNOLOGY	2017
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma	ONCOGENE	2017
The role of peroxiredoxins in cancer	MOLECULAR AND CLINICAL ONCOLOGY	2017
A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer	EBIOMEDICINE	2017
Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers	JOURNAL OF THE NATIONAL CANCER INSTITUTE	2017
Optimizing the identification of risk-relevant mutations by multigene panel testing in selected hereditary breast/ovarian cancer families	CANCER MEDICINE	2017
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of modifiers of BRCA1/2	BREAST CANCER RESEARCH	2016
Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene	CANCER	2016
Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH	2016
A MYCN-MRN complex axis controls replication stress for the safe expansion of neuroprogenitor cells	MOLECULAR & CELLULAR ONCOLOGY	2016
Proffered papers and posters presented at the Sixth International Symposium on Hereditary Breast and Ovarian Cancer— BRCA: Challenges and Opportunities	CURRENT ONCOLOGY	2016
Candidate genetic modifiers for breast and ovarian cancer risk inBRCA1andBRCA2 mutation carriers	CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION	2015
Validation of the Ion Torrent PGM sequencing for the prospective routine molecular diagnostic of colorectal cancer.	CLINICAL BIOCHEMISTRY	2015
Characterization of medulloblastoma in Fanconi Anemia: a novel mutation in the BRCA2 gene and SHH molecular subgroup	BIOMARKER RESEARCH	2015
The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress	CELL DEATH AND DIFFERENTIATION	2015

Progetti di Ricerca

Dissecting the role of the Nijmegen breakage syndrome protein in SHH-dependent tumorigenesis
Repressing or enhancing replication stress: the two sides of the coin to understand and tackle MYCN-dependent tumors.